Phenotypes for Pclaf Trp53 MGI:5302543 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Pclaf^tm1.1Lkd/Pclaf^tm1.1Lkd Trp53^tm1Tyj/Trp53⁺
Genetic Background	involves: 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pclaf^tm1.1Lkd mutation (0 available); any Pclaf mutation (8 available)
Trp53^tm1Tyj mutation (12 available); any Trp53 mutation (232 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

increased hematopoietic stem cell number ( J:177782 )

• lymphoid-primed multipotent progenitors are increased compared to in 2810417H13Rik^tm1.1Lkd homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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