Mouse Genome Informatics
tg
    Tg(CD2-Stat6*V625A*T626A)78Mhk/0
involves: C3H * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
behavior/neurological
• resulting in alopecia on the face, back, and other areas

homeostasis/metabolism
• 10 days after retinoic acid treatment, mice exhibit a 4-fold elevation in transepithelial water loss unlike similarly treated wild-type mice

immune system
• mice develop skin inflammation that is similar to atopic dermatitis unlike wild-type mice

integument
• 10 days after retinoic acid treatment, mice exhibit a 4-fold elevation in transepithelial water loss unlike similarly treated wild-type mice
• mice develop skin inflammation that is similar to atopic dermatitis unlike wild-type mice
• on the face, back, and other areas secondary to excessive scratching
• eosinophils and lymphocytes

Mouse Models of Human Disease
OMIM IDRef(s)
Dermatitis, Atopic 603165 J:160119