Phenotypes for Gt(ROSA)26Sor Telo2 Trp53 MGI:3819400 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Telo2^tm1Tdl/Telo2^tm1.1Tdl Trp53^tm1Tyj/Trp53^tm1Tyj Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺
Genetic Background	involves: 129 * 129P2/OlaHsd * 129S2/SvPas * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(cre/ERT)Nat} mutation (3 available); any Gt(ROSA)26Sor mutation (1062 available)
Telo2^tm1.1Tdl mutation (0 available); any Telo2 mutation (30 available)
Telo2^tm1Tdl mutation (0 available); any Telo2 mutation (30 available)
Trp53^tm1Tyj mutation (12 available); any Trp53 mutation (237 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal cell cycle ( J:141633 )

• tamoxifen-treated mouse embryonic fibroblasts exhibit cell cycle arrest after 6 days in culture unlike wild-type cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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