Phenotypes for Gfap Vim MGI:3621197 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gfap^tm1Pkny/Gfap^tm1Pkny Vim^tm1Cba/Vim^tm1Cba
Genetic Background	involves: 129/Sv * 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gfap^tm1Pkny mutation (0 available); any Gfap mutation (46 available)
Vim^tm1Cba mutation (2 available); any Vim mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal neuron differentiation ( J:106195 )

• in the granular layer of the dentate gyrus of 18-month old null mice, there is a 36% in formation of new neurons compared to wild-type

abnormal dentate gyrus morphology ( J:106195 )

• 18-month old null mice show higher levels of cell proliferation (34%) in the granular layer of the dentate gyrus than in wild-type

cellular

abnormal neuron differentiation ( J:106195 )

• in the granular layer of the dentate gyrus of 18-month old null mice, there is a 36% in formation of new neurons compared to wild-type

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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