All Phenotypes Dbn1<tm1b(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dbn1^{tm1b(KOMP)Wtsi}
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5501061

Summary

20 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}	C57BL/6NCrl-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi	MGI:7414858
hm2	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Bay	MGI:5756967
hm3	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/H	MGI:5756969
hm4	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ics	MGI:5756965
hm5	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ieg	MGI:5756964
hm6	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/J	MGI:5756968
hm7	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/MbpMmucd	MGI:6325128
hm8	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Rbrc	MGI:5756966
hm9	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ucd	MGI:5756970
hm10	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi	MGI:5631032
ht11	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺	C57BL/6NCrl-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi	MGI:7414857
ht12	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Bay	MGI:5767624
ht13	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/H	MGI:5756959
ht14	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ics	MGI:5756963
ht15	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ieg	MGI:5756961
ht16	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/J	MGI:5756962
ht17	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/MbpMmucd	MGI:7471968
ht18	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Rbrc	MGI:5759178
ht19	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ucd	MGI:5756960
ht20	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi	MGI:5608363

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6NCrl-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - CCP-IMG

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - CCP-IMG

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Bay
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

embryo

abnormal embryo size ( J:211773 )

IMPC - BCM

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - BCM

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - BCM

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/H
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ics
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ieg
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/J
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - JAX

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/MbpMmucd
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

microcephaly ( J:211773 )

IMPC - UCD

limbs/digits/tail

syndactyly ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Rbrc
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - RBRC

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ucd
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

dilated liver sinusoidal space ( J:239583 )

DMDD

craniofacial

abnormal hypoglossal canal morphology ( J:239583 )

DMDD

absent hypoglossal canal ( J:239583 )

DMDD

embryo

abnormal Wolffian duct connection ( J:239583 )

DMDD

liver/biliary system

dilated liver sinusoidal space ( J:239583 )

DMDD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - WTSI

nervous system

abnormal brain white matter morphology ( J:239583 )

DMDD

abnormal brain internal capsule morphology ( J:239583 )

DMDD

abnormal forebrain morphology ( J:239583 )

DMDD

abnormal telencephalon morphology ( J:239583 )

DMDD

abnormal brachial plexus formation ( J:239583 )

DMDD

absent hypoglossal nerve ( J:239583 )

DMDD

thin hypoglossal nerve ( J:239583 )

DMDD

skeleton

abnormal hypoglossal canal morphology ( J:239583 )

DMDD

absent hypoglossal canal ( J:239583 )

DMDD

abnormal cervical rib ( J:239583 )

DMDD

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺
Genetic Background	C57BL/6NCrl-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - CCP-IMG

enlarged heart ( J:211773 )

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

IMPC - CCP-IMG

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - CCP-IMG

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Bay
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

decreased vertical activity ( J:211773 )

IMPC - BCM

cardiovascular system

enlarged heart ( J:211773 )

IMPC - BCM

growth/size/body

enlarged heart ( J:211773 )

IMPC - BCM

homeostasis/metabolism

decreased circulating cholesterol level ( J:211773 )

IMPC - BCM

decreased circulating serum albumin level ( J:211773 )

IMPC - BCM

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/H
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal vertebrae morphology ( J:211773 )

IMPC - HAR

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ics
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - ICS

vision/eye

decreased total retina thickness ( J:211773 )

IMPC - ICS

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ieg
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

increased red blood cell distribution width ( J:211773 )

IMPC - HMGU

decreased mean platelet volume ( J:211773 )

IMPC - HMGU

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/J
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

increased lean body mass ( J:211773 )

IMPC - JAX

homeostasis/metabolism

decreased circulating free fatty acids level ( J:211773 )

IMPC - JAX

decreased circulating serum albumin level ( J:211773 )

IMPC - JAX

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/MbpMmucd
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

IMPC - UCD

growth/size/body

microcephaly ( J:211773 )

IMPC - UCD

limbs/digits/tail

syndactyly ( J:211773 )

IMPC - UCD

nervous system

increased prepulse inhibition ( J:211773 )

IMPC - UCD

skeleton

increased bone mineral content ( J:211773 )

IMPC - UCD

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Rbrc
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased exploration in new environment ( J:211773 )

IMPC - RBRC

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - RBRC

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ucd
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

IMPC - TCP

growth/size/body

increased lean body mass ( J:211773 )

IMPC - TCP

homeostasis/metabolism

increased circulating phosphate level ( J:211773 )

IMPC - TCP

skeleton

increased bone mineral content ( J:211773 )

IMPC - TCP

Allelic Composition	Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺
Genetic Background	C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi
Cell Lines	EPD0211_3_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbn1^{tm1b(KOMP)Wtsi} mutation (3 available); any Dbn1 mutation (43 available)

Data Sources

IMPC Data for Dbn1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

increased CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

homeostasis/metabolism

increased circulating creatinine level ( J:211773 )

IMPC - WTSI

increased circulating magnesium level ( J:211773 )

IMPC - WTSI

increased circulating chloride level ( J:211773 )

IMPC - WTSI

immune system

increased CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

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