Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr2e1tm1Rev mutation
(0 available);
any
Nr2e1 mutation
(32 available)
Nr2e1tm1Rtyu mutation
(0 available);
any
Nr2e1 mutation
(32 available)
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nervous system
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• isolated neural stem cells infected with a cre-expressing virus display an 80% reduction in proliferation
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cellular
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• isolated neural stem cells infected with a cre-expressing virus display an 80% reduction in proliferation
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr2e1tm1Rev mutation
(0 available);
any
Nr2e1 mutation
(32 available)
Tg(CAG-cre/Esr1*)5Amc mutation
(9 available)
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nervous system
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• three weeks of voluntary running results in an increased number of dividing cells in the brain
• reduced pool of neural stem cells
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behavior/neurological
N |
• contextual fear conditioning is normal
• tone-cued memory is normal
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cellular
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• three weeks of voluntary running results in an increased number of dividing cells in the brain
• reduced pool of neural stem cells
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr2e1tm1Rev mutation
(0 available);
any
Nr2e1 mutation
(32 available)
Tg(Nes-cre)1Kln mutation
(4 available)
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nervous system
vision/eye
N |
• visual function remains at 2-4 months
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behavior/neurological
N |
• contextual fear conditioning is normal
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• profoundly impaired in a Morris water maze test
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• deficient short term memory but normal long term memory in a Morris water maze
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