Ubr4tm1.1Nkt
Targeted Allele Detail
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Symbol: |
Ubr4tm1.1Nkt |
Name: |
ubiquitin protein ligase E3 component n-recognin 4; targeted mutation 1.1, Yoshihiro Nakatani |
MGI ID: |
MGI:5532331 |
Synonyms: |
p600- |
Gene: |
Ubr4 Location: Chr4:139107970-139216844 bp, + strand Genetic Position: Chr4, 70.66 cM
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Alliance: |
Ubr4tm1.1Nkt page
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Growth retardation in E9.5-E12.5 Ubr4tm1.1Nkt/Ubr4tm1.1Nkt embryos
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:203460
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Parent Cell Line: |
TC1/TC-1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 1. Cre-mediated recombination removed the neomycin resistance cassette and exon 1.
(J:203460)
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Generation of the Ubr4tm1.1Nkt allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ubr4 Mutation: |
247 strains or lines available
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Original: |
J:203460 Nakaya T, et al., p600 Plays Essential Roles in Fetal Development. PLoS One. 2013;8(6):e66269 |
All: |
1 reference(s) |
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