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Sat2 Gene Detail
Summary
  • Symbol
    Sat2
  • Name
    spermidine/spermine N1-acetyl transferase 2
  • Synonyms
    2610016A03Rik, SSAT2, SSAT-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916465
    NCBI Gene: 69215
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:69512850-69514696 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.86 cM, cytoband B4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    58 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916465
 protein coding gene Chr11:69512824-69514857 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018541
 protein coding gene Chr11:70074978-70076824 (+)
A/J MGP_AJ_G0018509
 protein coding gene Chr11:67436285-67438131 (+)
AKR/J MGP_AKRJ_G0018478
 protein coding gene Chr11:69447025-69448871 (+)
BALB/cJ MGP_BALBcJ_G0018481
 protein coding gene Chr11:67746639-67748485 (+)
C3H/HeJ MGP_C3HHeJ_G0018294
 protein coding gene Chr11:69466056-69467902 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018932
 protein coding gene Chr11:72198160-72200006 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016577
 protein coding gene Chr11:64358226-64360058 (+)
CAST/EiJ MGP_CASTEiJ_G0017849
 protein coding gene Chr11:69709701-69711550 (+)
CBA/J MGP_CBAJ_G0018267
 protein coding gene Chr11:75426778-75428624 (+)
DBA/2J MGP_DBA2J_G0018376
 protein coding gene Chr11:67017264-67019295 (+)
FVB/NJ MGP_FVBNJ_G0018366
 protein coding gene Chr11:66654192-66656038 (+)
LP/J MGP_LPJ_G0018446
 protein coding gene Chr11:70640789-70642635 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018389
 protein coding gene Chr11:76025843-76027689 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018974
 protein coding gene Chr11:69703647-69705493 (+)
PWK/PhJ MGP_PWKPhJ_G0017623
 protein coding gene Chr11:67665978-67668277 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017413
 protein coding gene Chr11:69519436-69521272 (+)
WSB/EiJ MGP_WSBEiJ_G0017903
 protein coding gene Chr11:69376537-69378383 (+)



Homology
more
  • Human Ortholog
    SAT2, spermidine/spermine N1-acetyltransferase family member 2
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SAT2, spermidine/spermine N1-acetyltransferase family member 2
  • Synonyms
    SSAT2, SSAT-2
  • Links
    NCBI Gene ID: 112483
    neXtProt AC: NX_Q96F10
    UniProt: Q96F10

  • Chr Location
    17p13.1; chr17:7626234-7627876 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Sat2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    7 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    17
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000069835 Ensembl Gene Model | MGI Sequence Detail 1847 C57BL/6J ±  kb
transcript ENSMUST00000108656 Ensembl | MGI Sequence Detail 968 Not Applicable  
polypeptide ENSMUSP00000104296 Ensembl | MGI Sequence Detail 170 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 2
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory