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Gene Expression Data
Assay Details
Assay
Reference: J:66266 Lewandoski M, et al., Fgf8 signalling from the AER is essential for normal limb development. Nat Genet. 2000 Dec;26(4):460-3
Assay type: RNA in situ
MGI Accession ID: MGI:7720851
Gene symbol: Bmp7
Gene name: bone morphogenetic protein 7
Probe: Bmp7 probe
Probe preparation: RNA
Results
Specimen 3f fl normal: embryonic day 10.5; Fgf8tm1.3Mrt/Fgf8+, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Present 3f fl normal
Specimen 3f fl mutant: embryonic day 10.5; Fgf8tm1.3Mrt/Fgf8tm1.4Mrt, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present Regionally restricted 3f fl mutant Slight elevation of expression in anterior-most apical ectodermal ridge.
TS17: forelimb bud mesenchyme Present Regionally restricted 3f fl mutant Slight forelimb-specific elevation in expression in anterior mesenchyme.
Specimen 3f hl normal: embryonic day 10.5; Fgf8tm1.3Mrt/Fgf8+, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: hindlimb bud Present 3f hl normal
Specimen 3f hl mutant: embryonic day 10.5; Fgf8tm1.3Mrt/Fgf8tm1.4Mrt, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: hindlimb bud Present 3f hl mutant Expression appeared relatively normal compared to control.
Specimen E11.5 fl mutant not shown: embryonic day 11.5; Fgf8tm1.3Mrt/Fgf8tm1.4Mrt, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present Expression appeared relatively normal compared to control.
Specimen E11.5 hl mutant not shown: embryonic day 11.5; Fgf8tm1.3Mrt/Fgf8tm1.4Mrt, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: hindlimb bud Present Expression appeared relatively normal compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory