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Gene Expression Data
Assay Details
Assay
Reference: J:233142 Hilton MJ, et al., Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat Med. 2008 Mar;14(3):306-14
Assay type: RNA in situ
MGI Accession ID: MGI:7593616
Gene symbol: Ibsp
Gene name: integrin binding sialoprotein
Probe: Ibsp probe
Probe preparation: Antisense RNA
Results
Specimen 3b WT: embryonic day 18.5; Notch1tm2Rko/Notch1tm2Rko, Notch2tm3Grid/Notch2tm3Grid (more )
Structure Cell Type Level Pattern Image Note
TS26: tibia osteoblast Present 3b Ibsp WT
Specimen 3b PNN: embryonic day 18.5; Notch1tm2Rko/Notch1tm1Con, Notch2tm3Grid/Notch2tm3Grid, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: tibia osteoblast Strong 3b Ibsp PNN Increased expression in the larger osteoblast population in the mutant.
Specimen S3e Control: embryonic day 18.5; Psen2tm1Bdes/Psen2tm1Bdes (more )
Structure Cell Type Level Pattern Image Note
TS26: tibia osteoblast Present S3e control
Specimen S3e PPS: embryonic day 18.5; Psen1tm2Shn/Psen1tm2Shn, Psen2tm1Bdes/Psen2tm1Bdes, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: tibia osteoblast Strong S3e PPS Increased expression in the larger osteoblast population in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory