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Gene Expression Data
Assay Details
Assay
Reference: J:338182 Gehlen-Breitbach S, et al., The Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development. Int J Oral Sci. 2023 Apr 6;15(1):16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7529095
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved caspase3
Detection system: Secondary antibody coupled to Cy3
Results
Specimen S6a ctrl: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Trace S6a aCasp3 ctrl
Specimen S6a Kat5delta/+: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0, Kat5tm1.1Ge/Kat5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Trace S6a aCasp3 Kat5delta/delta Slightly increased rates of cell death - not statistically significant.
Specimen S6a Kat5delta/delta: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0, Kat5tm1.1Ge/Kat5tm1.1Ge (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present S6a aCasp3 Kat5delta/+ Authors report increased rates of apoptosis.
Specimen S6a Ep400delta/+: embryonic day 9.5; Ep400tm3Fuku/Ep400+, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Trace S6a aCasp3 Ep400delta/+ Slightly increased rates of cell death - not statistically significant.
Specimen S6a Ep400delta/delta: embryonic day 9.5; Ep400tm3Fuku/Ep400tm3Fuku, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present S6a aCasp3 Ep400delta/delta Authors report increased rates of apoptosis.
Specimen S6b ctrl: embryonic day 10.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch Trace S6b aCasp3 ctrl
Specimen S6b Kat5delta/+: embryonic day 10.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0, Kat5tm1.1Ge/Kat5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch Trace S6b aCasp3 Kat5delta/+ Slightly increased rates of cell death - not statistically significant.
Specimen S6b Kat5delta/delta: embryonic day 10.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0, Kat5tm1.1Ge/Kat5tm1.1Ge (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch Present S6b aCasp3 Kat5delta/delta Authors report increased rates of apoptosis.
Specimen S6b Ep400delta/+: embryonic day 10.5; Ep400tm3Fuku/Ep400+, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch Trace S6b aCasp3 Ep400delta/+ Slightly increased rates of cell death - not statistically significant.
Specimen S6b Ep400delta/delta: embryonic day 10.5; Ep400tm3Fuku/Ep400tm3Fuku, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch Present S6b aCasp3 Ep400delta/delta Authors report increased rates of apoptosis.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory