Kat5^tm1.1Ge
Targeted Allele Detail

Summary

• Symbol: Kat5^tm1.1Ge
• Name: K(lysine) acetyltransferase 5; targeted mutation 1.1, Gregor Eichele
• MGI ID: MGI:6356678
• Synonyms: Tip60^flox
• Gene: Kat5 Location: Chr19:5653042-5660265 bp, - strand Genetic Position: Chr19, 4.34 cM
• Alliance: Kat5^tm1.1Ge page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:277685
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 1-9 were flanked by loxP sites and an frt-flanked neomycin selection cassette. The neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:277685, J:287294)

Expression

In Mice Carrying this Mutation:

12 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kat5 Mutation: 25 strains or lines available

References

• Original: J:277685 Petkau N, et al., Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters. Elife. 2019 Jul 11;8:e43235
• All: 3 reference(s)