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Gene Expression Data
Assay Details
Assay
Reference: J:302538 Ulmke PA, et al., Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling. Development. 2021 Feb 8;148(3):dev188276
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7490325
Gene symbol: Elavl3
Gene name: ELAV like RNA binding protein 3
Antibody: anti-HuCD
Detection system: Secondary antibody
Results
Specimen S2C Control: embryonic day 11.5 (more )
Note: Double labeled: magenta - Elavl3 and Elavl4; green - Pax6 (assay MGI:7490324).
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted S2C Control Expression in immature neurons.
TS19: midbrain Present Regionally restricted S2C Control Expression in immature neurons.
TS19: telencephalon Present Regionally restricted S2C Control Expression in dorsolateral part of telencephalon.
Specimen S2C cKO: embryonic day 11.5; Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: magenta - Elavl3 and Elavl4; green - Pax6 (assay MGI:7490324).
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted S2C cKO Expression in immature neurons.
TS19: midbrain Present Regionally restricted S2C cKO Expression in immature neurons.
TS19: telencephalon Absent S2C cKO
Specimen 3A Rostral Control: embryonic day 13.5 (more )
Note: Double labeled: green - Elavl3 and Elavl4; red - Pax6 (assay MGI:7490324).
Structure Level Pattern Image Note
TS21: cortical plate Present Regionally restricted 3A Rostral Control (upper) , 3A Rostral Control (lower) Expression in immature neurons.
Specimen 3A Rostral cKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant. Double labeled: green - Elavl3 and Elavl4; red - Pax6 (assay MGI:7490324).
Structure Level Pattern Image Note
TS21: cortical plate Weak Regionally restricted 3A Rostral cKO (lower) , 3A Rostral cKO (upper) Diminished number of expressing neurons compared to control
Specimen 3A Caudal Control: embryonic day 13.5 (more )
Note: Double labeled: green - Elavl3 and Elavl4; red - Pax6 (assay MGI:7490324).
Structure Level Pattern Image Note
TS21: cortical plate Present Regionally restricted 3A Caudal Control (lower) , 3A Caudal Control (upper) Expression in immature neurons.
Specimen 3A Caudal cKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant. Double labeled: green - Elavl3 and Elavl4; red - Pax6 (assay MGI:7490324).
Structure Level Pattern Image Note
TS21: cortical plate Weak Regionally restricted 3A Caudal cKO (lower) , 3A Caudal cKO (upper) Diminished number of expressing neurons compared to control
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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