About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:302538 Ulmke PA, et al., Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling. Development. 2021 Feb 8;148(3):dev188276
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7490324
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6
Detection system: Secondary antibody
Results
Specimen S2C Control: embryonic day 11.5 (more )
Note: Double labeled: green - Pax6; magenta - Elavl3 (assay MGI:7490325) and Elavl4 (assay MGI:7490326).
Structure Level Pattern Image Note
TS19: diencephalon Present S2C Control Expression in primordial neural stem cells.
TS19: midbrain Present S2C Control Expression in primordial neural stem cells.
TS19: telencephalon Present S2C Control Expression in dorsolateral part of telencephalon,
Specimen S2C cKO: embryonic day 11.5; Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: green - Pax6; magenta - Elavl3 (assay MGI:7490325) and Elavl4 (assay MGI:7490326).
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted S2C cKO Expression in primordial neural stem cells.
TS19: midbrain Present Regionally restricted S2C cKO Expression in primordial neural stem cells.
TS19: telencephalon Absent S2C cKO
Specimen 3A Rostral Control: embryonic day 13.5 (more )
Note: Double labeled: red - Pax6; green - Elavl3 (assay MGI:7490325) and Elavl4 (assay MGI:7490326).
Structure Level Pattern Image Note
TS21: cerebral cortex ventricular layer Present Regionally restricted 3A Rostral Control (upper) , 3A Rostral Control (lower) Expression in apical progenitors.
Specimen 3A Rostral cKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant. Double labeled: red - Pax6; green - Elavl3 (assay MGI:7490325) and Elavl4 (assay MGI:7490326).
Structure Level Pattern Image Note
TS21: cerebral cortex ventricular layer Present Regionally restricted 3A Rostral cKO (lower) , 3A Rostral cKO (upper) Expression in apical progenitors comparable to control.
Specimen 3A Caudal Control: embryonic day 13.5 (more )
Note: Double labeled: red - Pax6; green - Elavl3 (assay MGI:7490325) and Elavl4 (assay MGI:7490326).
Structure Level Pattern Image Note
TS21: cerebral cortex ventricular layer Present Regionally restricted 3A Caudal Control (lower) , 3A Caudal Control (upper) Expression in apical progenitors.
Specimen 3A Caudal cKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant. Double labeled: red - Pax6; green - Elavl3 (assay MGI:7490325) and Elavl4 (assay MGI:7490326).
Structure Level Pattern Image Note
TS21: cerebral cortex ventricular layer Present Regionally restricted 3A Caudal cKO (upper) , 3A Caudal cKO (lower) Expression in apical progenitors comparable to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory