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Gene Expression Data
Assay Details
Assay
Reference: J:316204 Chen Z, et al., Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart. Cardiovasc Res. 2018 Jun 1;114(7):965-978
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7449007
Gene symbol: Ggps1
Gene name: geranylgeranyl diphosphate synthase 1
Antibody: anti-GGPS1 (14944-1-AP)
Detection system: Secondary antibody
Assay notes: Multiple Ggps1 antibodies were described, but the one used in this assay was not detailed. Anti-GGPS1 MGI:7448882 may have been used in this assay.
Results
Specimen 1A E8.5: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: common atrial chamber Present Regionally restricted 1A E8.5 (right) , 1A E8.5 (left) Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.
TS13: primitive ventricle Present Regionally restricted 1A E8.5 (right) , 1A E8.5 (left) Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.

Specimen 1A E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: common atrial chamber Present Regionally restricted 1A E9.5 (left) , 1A E9.5 (right) Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.
TS15: primitive ventricle Present Regionally restricted 1A E9.5 (left) , 1A E9.5 (right) Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.

Specimen 1A E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: common atrial chamber Present Regionally restricted 1A E10.5 (left) , 1A E10.5 (right) Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.
TS17: primitive ventricle Present Regionally restricted 1A E10.5 (left) , 1A E10.5 (right) Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.

Specimen 1A E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: heart atrium Present Regionally restricted 1A E11.5 (right) , 1A E11.5 (left) Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.
TS19: heart ventricle Present Regionally restricted 1A E11.5 (right) , 1A E11.5 (left) Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.

Specimen 1A E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart atrium Present Regionally restricted 1A E12.5 (left) , 1A E12.5 (right) present / RR
TS20: heart ventricle Present Regionally restricted 1A E12.5 (left) , 1A E12.5 (right) present / RR

Specimen 1A E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: heart atrium Present Regionally restricted 1A E13.5 (right) , 1A E13.5 (left) Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.
TS21: heart ventricle Present Regionally restricted 1A E13.5 (right) , 1A E13.5 (left) Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.

Specimen 1A E15..5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: heart atrium Present Regionally restricted 1A E15.5 Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.
TS23: heart ventricle Present Regionally restricted 1A E15.5 Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.

Specimen 1A E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: heart atrium Present Regionally restricted 1A E18.5 Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.
TS26: heart ventricle Present Regionally restricted 1A E18.5 Expression in both atria and ventricles continuously from E8.5 to E18.5, but lower in endocardial cushion than in compact zone and trabecula.

Specimen S3C Control: embryonic day 9.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS15: heart Present S3C Control (upper) , S3C Control (lower)
TS15: outflow tract Present S3C Control (upper) , S3C Control (lower)

Specimen S3C Cre/+: embryonic day 9.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: outflow tract Absent S3C Cre/+ (upper) , S3C Cre/+ (lower) Authors report Ggpps was deleted at E9.5.
TS15: primitive ventricle Absent S3C Cre/+ (upper) , S3C Cre/+ (lower) Authors report Ggpps was deleted at E9.5.

Specimen S3F E13.5 Control: embryonic day 13.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS21: heart atrium Present S3F E13.5 Control
TS21: heart ventricle Present S3F E13.5 Control

Specimen S3F E13.5 aSMA-Cre: embryonic day 13.5; Ggps1tm1Licj/Ggps1tm1Licj, Tg(Acta2-cre)#Xya/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: heart atrium Absent S3F E13.5 a-SMA-Cre Authors report Ggpps was deleted at E13.5.
TS21: heart ventricle Absent S3F E13.5 a-SMA-Cre Authors report Ggpps was deleted at E13.5.

Specimen S3F E15.5 Control: embryonic day 15.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS23: heart atrium Present S3F E15.5 Control
TS23: heart ventricle Present S3F E15.5 Control

Specimen S3F aSMA-Cre: embryonic day 15.5; Ggps1tm1Licj/Ggps1tm1Licj, Tg(Acta2-cre)#Xya/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: heart atrium Absent S3F E15.5 a-SMA-Cre
TS23: heart ventricle Absent S3F E15.5 a-SMA-Cre


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory