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Gene Expression Data
Assay Details
Assay
Reference: J:158780 Li S, et al., SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells. BMC Dev Biol. 2010;10:19
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6479960
Gene symbol: Sel1l
Gene name: sel-1 suppressor of lin-12-like (C. elegans)
Reporter: lacZ
Antibody: anti-B-galactosidase
Results
Specimen 1A: embryonic day 12.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Sox9 (assay MGI:6479962).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Regionally restricted 1A Expression in small number of cells within core of Sox9-expressing pancreatic epithelium.
Specimen 1B: embryonic day 12.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Sox9 (assay MGI:6479962).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Regionally restricted 1B No co-expression with Sox9.
Specimen 1C: embryonic day 12.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Glu (Gcg assay MGI:6479963).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Regionally restricted 1C Co-expression with glucagon.
Specimen 1D: embryonic day 12.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Ins1 (assay MGI:6479964) and Ins2 (assay MGI:6479965).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Regionally restricted 1D Co-expression with insulin.
Specimen 1E: embryonic day 14.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Pdx1 (assay MGI:6479966).
Structure Level Pattern Image Note
TS22: pancreas epithelium Present Graded 1E High expression in epithelial branches; no or very low expression in core "duct-like" epithelium.
Specimen 1F: embryonic day 14.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Sox9 (assay MGI:6479962).
Structure Level Pattern Image Note
TS22: pancreas epithelium Present Regionally restricted 1F Very low expression in core epithelial cells expressing Sox9.
Specimen 1G: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Amy (assay MGI:6479967).
Structure Level Pattern Image Note
TS23: pancreas epithelium Strong Regionally restricted 1G High expression in core pancreatic epithelium.
Specimen 1H: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Amy (assay MGI:6479967).
Structure Level Pattern Image Note
TS23: pancreas epithelium Strong Regionally restricted 1H High expression in core pancreatic epithelium.
Specimen 1I: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Glu (Gcg assay MGI:6479963).
Structure Level Pattern Image Note
TS23: pancreas epithelium Present Regionally restricted 1I Expression co-localizes with glucagon.
Specimen 1J: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Ins1 (assay MGI:6479964) and Ins2 (assay MGI:6479965).
Structure Level Pattern Image Note
TS23: pancreas epithelium Present Regionally restricted 1J Expression co-localizes with insulin.
Specimen 1K: postnatal day 1; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Glu (Gcg assay MGI:6479963).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present 1K Expression in both islet and acinar cells.
TS27: pancreatic acinus Present 1K Expression in both islet and acinar cells.
Specimen 1L: postnatal day 1; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: red - Sel1l reporter; green - Pdx1 (assay MGI:6479966).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present Regionally restricted 1L Expression co-localizes with Pdx1 in islet cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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