Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Del(1Lefty2-Lefty1)1Hmd
Name:	deletion, Chr 1, Hiroshi Hamada 1
MGI ID:	MGI:6470413
Synonyms:	Del(1Lefty2-Lefty1)1Brre
Gene:	Del(1Lefty2-Lefty1)1Hmd  Location: unknown  Genetic Position: Chr1, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:257216
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intergenic deletion, Intragenic deletion   Del(1Lefty2-Lefty1)1Hmd involves 3 genes/genome features (Lefty2, Pycr2, Lefty1) View all   Mutation details: A loxP site was inserted upstream of Lefty2 (Igs52) and a second loxP site downstream of Lefty1 (Igs53). Lefty2, Pycr2 and Lefty1 were deleted through subsequent cre-mediated recombination. (J:257216)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Del(1Lefty2-Lefty1)1Hmd Mutation:	0 strains or lines available

Original:	J:257216 Takaoka K, et al., Both Nodal signalling and stochasticity select for prospective distal visceral endoderm in mouse embryos. Nat Commun. 2017 Nov 14;8(1):1492
All:	2 reference(s)