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Gene Expression Data
Assay Details
Assay
Reference: J:232100 Huang Z, et al., Neogenin Promotes BMP2 Activation of YAP and Smad1 and Enhances Astrocytic Differentiation in Developing Mouse Neocortex. J Neurosci. 2016 May 25;36(21):5833-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6452173
Gene symbol: Rbfox3
Gene name: RNA binding protein, fox-1 homolog (C. elegans) 3
Antibody: Anti-NeuN (clone A60; MAB377)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4A +/+: postnatal day 1 (more )
Note: Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS27: neocortex Present 4A upper left , 4A upper NeuN , 4A upper merge

Specimen 4A m/m: postnatal day 1; Neo1Gt(KST265)Byg/Neo1Gt(KST265)Byg (more )
Note: Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS27: neocortex Present 4A lower NeuN , 4A lower merge , 4A lower left Same as in the wild-type.

Specimen 4B +/+: postnatal day 1 (more )
Note: Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS27: hippocampus Present 4B upper NeuN , 4B upper left , 4B upper merge

Specimen 4B m/m: postnatal day 1; Neo1Gt(KST265)Byg/Neo1Gt(KST265)Byg (more )
Note: Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS27: hippocampus Present 4B lower NeuN , 4B lower merge , 4B lower left Same as in the wild-type.

Specimen 7A f/f: postnatal day 1; Neo1tm1.1Wcx/Neo1tm1.1Wcx (more )
Note: Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS27: neocortex Present 7A upper merge , 7A upper NeuN , 7A upper left

Specimen 7A Nes-CKO: postnatal day 1; Neo1tm1.1Wcx/Neo1tm1.1Wcx, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS27: neocortex Present 7A lower merge , 7A lower NeuN , 7A lower left Same as in the wild-type.

Specimen 7B f/f: postnatal day 1; Neo1tm1.1Wcx/Neo1tm1.1Wcx (more )
Note: Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS27: hippocampus Present 7B upper NeuN , 7B upper merge , 7B upper left

Specimen 7B Nes-CKO: postnatal day 1; Neo1tm1.1Wcx/Neo1tm1.1Wcx, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS27: hippocampus Present 7B lower left , 7B lower merge , 7B lower NeuN Same as in the wild-type.

Specimen 7E f/f: postnatal day 3; Neo1tm1.1Wcx/Neo1tm1.1Wcx (more )
Note: Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS27: neocortex Present 7E upper left , 7E upper right

Specimen 7E GFAP-CKO: postnatal day 3; Neo1tm1.1Wcx/Neo1tm1.1Wcx, Tg(GFAP-cre)25Mes/0 (more )
Note: Conditional mutant. Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS27: neocortex Present 7E lower left , 7E lower right Same as in the wild-type.

Specimen 7F f/f: postnatal day 10; Neo1tm1.1Wcx/Neo1tm1.1Wcx (more )
Note: Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS28: neocortex Present 7F upper right , 7F upper left

Specimen 7F Nex-CKO: postnatal day 10; Neo1tm1.1Wcx/Neo1tm1.1Wcx, Neurod6tm1(cre)Kan/Neurod6+ (more )
Note: Conditional mutant. Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS28: neocortex Present 7F lower left , 7F lower right Same as in the wild-type.

Specimen 13A Neo +/+: postnatal day 7 (more )
Note: Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS28: neocortex Present 13A-1 upper

Specimen 13A Neo +/-: postnatal day 7; Neo1Gt(KST265)Byg/Neo1+ (more )
Note: Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS28: neocortex Present 13A-2 upper

Specimen 13A YAP-f/w Nestin: postnatal day 7; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1+ (more )
Note: Conditional mutant. Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS28: neocortex Present 13A-3 upper

Specimen 13A Neo+/- YAP-f/w Nestin: postnatal day 7; Neo1Gt(KST265)Byg/Neo1+, Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1+ (more )
Note: Conditional mutant. Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS28: neocortex Present 13A-4 upper

Specimen 13A YAP Nestin-CKO: postnatal day 7; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant. Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS28: neocortex Present 13A-5 upper

Specimen 13C Yap f/f: postnatal day 7; Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS28: hippocampus Present 13C left

Specimen 13C YAP Nestin-CKO: postnatal day 7; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant. Double labeled: red - Rbfox3; green - Fabp7 (assay MGI:6452169).
Structure Level Pattern Image Note
TS28: hippocampus Present 13C right


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory