Neo1^tm1.1Wcx
Targeted Allele Detail

Summary

• Symbol: Neo1^tm1.1Wcx
• Name: neogenin; targeted mutation 1.1, Wen-Cheng Xiong
• MGI ID: MGI:6258431
• Synonyms: Neo^f, neogenin^f
• Gene: Neo1 Location: Chr9:58781970-58943724 bp, - strand Genetic Position: Chr9, 31.81 cM
• Alliance: Neo1^tm1.1Wcx page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232100
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the exon 4, and an frt flanked neo cassette and another loxP site was inserted downstream of the exon 4. Flp mediated recombination removed the neo cassette leaving the coding exon floxed. (J:232100)

Expression

In Mice Carrying this Mutation:

50 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Neo1 Mutation: 63 strains or lines available

References

• Original: J:232100 Huang Z, et al., Neogenin Promotes BMP2 Activation of YAP and Smad1 and Enhances Astrocytic Differentiation in Developing Mouse Neocortex. J Neurosci. 2016 May 25;36(21):5833-49
• All: 7 reference(s)