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Gene Expression Data
Assay Details
Assay
Reference: J:127471 Wang S, et al., Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse. Mech Dev. 2007 Nov-Dec;124(11-12):898-910
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6449810
Gene symbol: Ppy
Gene name: pancreatic polypeptide
Antibody: anti-PP
Results
Specimen 1C1: embryonic day 15.5 (more )
Note: Double labeled: green - Ppy; red - Myt1 (assay MGI:6449800).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present 1C1

Specimen 1C2: postnatal week 12 (more )
Note: Double labeled: green - Ppy; red - Myt1 (assay MGI:6449800).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 1C2

Specimen 1C2 inset: postnatal week 12 (more )
Note: Double labeled: green - Ppy; red - Myt1 (assay MGI:6449800).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 1C2 inset

Specimen 5A1: embryonic day 15.5 (more )
Note: Double labeled: green - Ppy; red - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 5A1 Substantial number of cells co-express Ppy and insulin.

Specimen 5A2: embryonic day 15.5; Myt1tm1.1Ggu/Myt1+ (more )
Note: Double labeled: green - Ppy; red - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 5A2 Substantial number of cells co-express Ppy and insulin.

Specimen 5A3: embryonic day 15.5; Myt1tm1.1Ggu/Myt1tm1.1Ggu (more )
Note: Double labeled: green - Ppy; red - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 5A3 Substantial number of cells co-express Ppy and insulin.

Specimen 5A3 inset: embryonic day 15.5; Myt1tm1.1Ggu/Myt1tm1.1Ggu (more )
Note: Double labeled: green - Ppy; red - Sst (assay MGI:6449811).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present 5A3 inset (left)

Specimen 5B1: embryonic day 15.5 (more )
Note: Double labeled: green - Ppy; red - Sst (assay MGI:6449811).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 5B1 Substantial number of cells co-express Ppy and Sst.

Specimen 5B2: embryonic day 15.5; Myt1tm1.1Ggu/Myt1+ (more )
Note: Double labeled: green - Ppy; red - Sst (assay MGI:6449811).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 5B2 Substantial number of cells co-express Ppy and Sst.

Specimen 5B3: embryonic day 15.5; Myt1tm1.1Ggu/Myt1tm1.1Ggu (more )
Note: Double labeled: green - Ppy; red - Sst (assay MGI:6449811).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 5B3 Substantial number of cells co-express Ppy and Sst.

Specimen 5C1: embryonic day 18.5 (more )
Note: Double labeled: green - Ppy; red - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted 5C1 Substantial number of cells co-express Ppy and insulin.

Specimen 5C2: embryonic day 18.5; Myt1tm1.1Ggu/Myt1+ (more )
Note: Double labeled: green - Ppy; red - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted 5C2 Substantial number of cells co-express Ppy and insulin.

Specimen 5C3: embryonic day 18.5; Myt1tm1.1Ggu/Myt1tm1.1Ggu (more )
Note: Double labeled: green - Ppy; red - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted 5C3 Substantial number of cells co-express Ppy and insulin.

Specimen 5C3 inset: embryonic day 18.5; Myt1tm1.1Ggu/Myt1tm1.1Ggu (more )
Note: Double labeled: green - Ppy; red - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present 5C3 inset (left)

Specimen 5D1: embryonic day 18.5 (more )
Note: Double labeled: green - Ppy; red - Sst (assay MGI:6449811).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted 5D1 Substantial number of cells co-express Ppy and Sst.

Specimen 5D2: embryonic day 18.5; Myt1tm1.1Ggu/Myt1+ (more )
Note: Double labeled: green - Ppy; red - Sst (assay MGI:6449811).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted 5D2 Substantial number of cells co-express Ppy and Sst.

Specimen 5D3: embryonic day 18.5; Myt1tm1.1Ggu/Myt1tm1.1Ggu (more )
Note: Double labeled: green - Ppy; red - Sst (assay MGI:6449811).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted 5D3 Substantial number of cells co-express Ppy and Sst.

Specimen 6B: postnatal adult; Myt1tm1Ggu/Myt1tm1.1Ggu, Tg(Pdx1-cre)89.1Dam/? (more )
Note: Conditional mutant. Triple labeled: green - Ppy; blue - Mafa (assay MGI:6449813); red - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present Regionally restricted 6B PP , 6B merge Expression in cells that are not mature beta cells.

Specimen 6D: postnatal adult; Myt1tm1Ggu/Myt1tm1.1Ggu, Tg(Pdx1-cre)89.1Dam/? (more )
Note: Conditional mutant. Triple labeled: green -Ppy; blue - Mafb (assay MGI:6449814); red - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present Regionally restricted 6D merge , 6D PP Expression in cells that are not mature beta cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory