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Gene Expression Data
Assay Details
Assay
Reference: J:200791 Wakaoka T, et al., Tracing Sox10-expressing cells elucidates the dynamic development of the mouse inner ear. Hear Res. 2013 Aug;302:17-25
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6438107
Gene symbol: Myo6
Gene name: myosin VI
Antibody: anti-Myo6 (25-6791)
Detection system: Secondary antibody coupled to Texas Red
Results
Specimen 5B: postnatal day 21; Sox10tm1Takk/Sox10+ (more )
Note: Double labeled: red - Myo6; green - Sox10 reporter (assay MGI:6438102)
Structure Level Pattern Image Note
TS28: cochlea epithelium Present Single cells 5B Expression is seen in hair cells.
Specimen 5D: postnatal day 21; Sox10tm1Takk/Sox10+ (more )
Note: Double labeled: red - Myo6; green - Sox10 reporter (assay MGI:6438102)
Structure Level Pattern Image Note
TS28: vestibular epithelium Present Single cells 5D Expression is seen in hair cells.
Specimen 5F/G: postnatal day 21; Sox10tm1Takk/Sox10+ (more )
Note: Double labeled: red - Myo6; green - Sox10 reporter (assay MGI:6438102)
Structure Level Pattern Image Note
TS28: organ of Corti Present Single cells 5F , 5G Expression is seen in inner and outer hair cells.
Specimen 6A'/A'': embryonic day 15.5; Sox10tm1Takk/Sox10+ (more )
Note: Double labeled: red - Myo6; green - Sox10 reporter (assay MGI:6438102)
Structure Level Pattern Image Note
TS23: cochlea epithelium Absent 6A'' , 6A' In the apical turn (where the more immature hair cells are located), no expression is seen.
Specimen 6B'/B'': embryonic day 15.5; Sox10tm1Takk/Sox10+ (more )
Note: Double labeled: red - Myo6; green - Sox10 reporter (assay MGI:6438102)
Structure Level Pattern Image Note
TS23: cochlea epithelium Present Single cells 6B' , 6B'' In the middle turn, expression was seen in a presumptive inner hair cell.
Specimen 6C'/C'': embryonic day 15.5; Sox10tm1Takk/Sox10+ (more )
Note: Double labeled: red - Myo6; green - Sox10 reporter (assay MGI:6438102)
Structure Level Pattern Image Note
TS23: cochlea epithelium Present Regionally restricted 6C' , 6C'' In the basal turn, expression was seen in rows of cells believed to be inner and outer hair cells.
Specimen 6D'/D'': embryonic day 15.5 (more )
Note: Double labeled: red - Myo6; green - Sox10 protein (assay MGI:6438112)
Structure Level Pattern Image Note
TS23: cochlea epithelium Absent 6D'' , 6D' In the apical turn (where the more immature hair cells are located), no expression is seen.
Specimen 6E'/E'': embryonic day 15.5 (more )
Note: Double labeled: red - Myo6; green - Sox10 protein (assay MGI:6438112)
Structure Level Pattern Image Note
TS23: cochlea epithelium Present Single cells 6E'' , 6E' In the middle turn, expression was seen in a presumptive inner hair cell.
Specimen 6F'/F'': embryonic day 15.5 (more )
Note: Double labeled: red - Myo6; green - Sox10 protein (assay MGI:6438112)
Structure Level Pattern Image Note
TS23: cochlea epithelium Present Regionally restricted 6F'' , 6F' In the basal turn, expression was seen in rows of cells believed to be inner and outer hair cells.
Specimen 7A'/A'': embryonic day 16.5; Sox10tm1Takk/Sox10+ (more )
Note: Double labeled: red - Myo6; green - Sox10 reporter (assay MGI:6438102)
Structure Level Pattern Image Note
TS24: organ of Corti Present Single cells 7A' , 7A'' In the apical turn, expression is seen in presumptive inner hair cells.
Specimen 7B'/B'': embryonic day 16.5; Sox10tm1Takk/Sox10+ (more )
Note: Double labeled: red - Myo6; green - Sox10 reporter (assay MGI:6438102)
Structure Level Pattern Image Note
TS24: organ of Corti Present Single cells 7B' , 7B'' In the mid-apical turn, expression is seen in presumptive inner hair cells.
Specimen 7C'/C'': embryonic day 16.5; Sox10tm1Takk/Sox10+ (more )
Note: Double labeled: red - Myo6; green - Sox10 reporter (assay MGI:6438102)
Structure Level Pattern Image Note
TS24: organ of Corti Present Regionally restricted 7C' , 7C'' In the mid-basal turn, expression is seen in presumptive inner and outer hair cells.
Specimen 7D'/D'': embryonic day 16.5; Sox10tm1Takk/Sox10+ (more )
Note: Double labeled: red - Myo6; green - Sox10 reporter (assay MGI:6438102)
Structure Level Pattern Image Note
TS24: organ of Corti Present Regionally restricted 7D' , 7D'' In the basal turn, expression is seen in presumptive inner and outer hair cells.
Specimen 7E'/E'': embryonic day 16.5 (more )
Note: Double labeled: red - Myo6; green - Sox10 protein (assay MGI:6438112)
Structure Level Pattern Image Note
TS24: organ of Corti Present Single cells 7E'' , 7E' In the apical turn, expression is seen in presumptive inner hair cells.
Specimen 7F'/F'': embryonic day 16.5 (more )
Note: Double labeled: red - Myo6; green - Sox10 protein (assay MGI:6438112)
Structure Level Pattern Image Note
TS24: organ of Corti Present Single cells 7F'' , 7F' In the mid-apical turn, expression is seen in presumptive inner hair cells.
Specimen 7G'/G'': embryonic day 16.5 (more )
Note: Double labeled: red - Myo6; green - Sox10 protein (assay MGI:6438112)
Structure Level Pattern Image Note
TS24: organ of Corti Present Regionally restricted 7G' , 7G'' In the mid-basal turn, expression is seen in presumptive inner and outer hair cells.
Specimen 7H'/H'': embryonic day 16.5 (more )
Note: Double labeled: red - Myo6; green - Sox10 protein (assay MGI:6438112)
Structure Level Pattern Image Note
TS24: organ of Corti Present Regionally restricted 7H' , 7H'' In the basal turn, expression is seen in presumptive inner and outer hair cells.
Specimen S2A'/A'': embryonic day 12.5; Sox10tm1Takk/Sox10+ (more )
Note: Double labeled: red - Myo6; green - Sox10 reporter (assay MGI:6438102)
Structure Level Pattern Image Note
TS20: vestibular component epithelium Present Single cells S2A'' , S2A' In the vestibule, expression is seen in presumptive hair cells.
Specimen S2B'/B'': embryonic day 12.5 (more )
Note: Double labeled: red - Myo6; green - Sox10 protein (assay MGI:6438112)
Structure Level Pattern Image Note
TS20: vestibular component epithelium Present Single cells S2B'' , S2B' In the vestibule, expression is seen in presumptive hair cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
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