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Sox10tm1Takk
Targeted Allele Detail
Summary
Symbol: Sox10tm1Takk
Name: SRY (sex determining region Y)-box 10; targeted mutation 1, Takahiro Kunisada
MGI ID: MGI:5805222
Synonyms: Sox10-IRES-Venus
Gene: Sox10  Location: Chr15:79039113-79048690 bp, - strand  Genetic Position: Chr15, 37.7 cM
Alliance: Sox10tm1Takk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:234904
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
    An IRES-Venus and neomycin resistance cassette were inserted downstream of the stop codon in exon 5. (J:234904)
Expression
In Mice Carrying this Mutation: 90 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox10 Mutation:  33 strains or lines available
References
Original:  J:234904 Motohashi T, et al., Neural crest cells retain their capability for multipotential differentiation even after lineage-restricted stages. Dev Dyn. 2011 Jul;240(7):1681-93
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory