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Gene Expression Data
Assay Details
Assay
Reference: J:200791 Wakaoka T, et al., Tracing Sox10-expressing cells elucidates the dynamic development of the mouse inner ear. Hear Res. 2013 Aug;302:17-25
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6438112
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Antibody: anti-Sox10 (N-20, sc-17342)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 6D/D'/D'': embryonic day 15.5 (more )
Note: Double labeled: green - Sox10; red - Myo6 (assay MGI:6438107)
Structure Level Pattern Image Note
TS23: cochlea Present 6D' , 6D , 6D'' Expression is seen in the apical turn.

Specimen 6E/E'/E'': embryonic day 15.5 (more )
Note: Double labeled: green - Sox10; red - Myo6 (assay MGI:6438107)
Structure Level Pattern Image Note
TS23: cochlea Present 6E' , 6E , 6E'' Expression is seen in the middle turn, including in presumptive inner hair cells.

Specimen 6F/F'/F'': embryonic day 15.5 (more )
Note: Double labeled: green - Sox10; red - Myo6 (assay MGI:6438107)
Structure Level Pattern Image Note
TS23: cochlea Present 6F , 6F'' , 6F' Expression is seen in the basal turn, including in inner (but not outer) hair cells.

Specimen 7E/E'/E'': embryonic day 16.5 (more )
Note: Double labeled: green - Sox10; red - Myo6 (assay MGI:6438107)
Structure Level Pattern Image Note
TS24: organ of Corti Present 7E'' , 7E' , 7E Expression is seen in the apical turn, including in presumptive inner hair cells.

Specimen 7F/F'/F'': embryonic day 16.5 (more )
Note: Double labeled: green - Sox10; red - Myo6 (assay MGI:6438107)
Structure Level Pattern Image Note
TS24: organ of Corti Present 7F , 7F'' , 7F' Expression is seen in the mid-apical turn, including in presumptive inner hair cells.

Specimen 7G/G'/G'': embryonic day 16.5 (more )
Note: Double labeled: green - Sox10; red - Myo6 (assay MGI:6438107)
Structure Level Pattern Image Note
TS24: organ of Corti Present 7G , 7G'' , 7G' Expression is seen in the mid-basal turn, including in presumptive inner (but not outer) hair cells.

Specimen 7H/H'/H'': embryonic day 16.5 (more )
Note: Double labeled: green - Sox10; red - Myo6 (assay MGI:6438107)
Structure Level Pattern Image Note
TS24: organ of Corti Present 7H , 7H' , 7H'' Expression is seen in the basal turn, although it is not seen in the presumptive inner and outer hair cells.

Specimen S1A/B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: otocyst Present Widespread S1A/B Staining is present in all cells.

Specimen S1C/D: postnatal day 1 (more )
Note: Double labeled: green - Sox10; red - Myo7a (assay MGI:6438104)
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted S1C , S1D Expression is seen in the supporting cells, not the hair cells or mesenchymal cells.
TS27: inner ear Present Single cells S1D , S1C Expression is seen in melanocytes or intermediate cells.

Specimen S1E/F: postnatal day 1 (more )
Note: Double labeled: green - Sox10; red - Myo7a (assay MGI:6438104)
Structure Level Pattern Image Note
TS27: vestibular epithelium Present Regionally restricted S1E , S1F Expression is seen in the supporting cells, not the hair cells.

Specimen S2B/B'/B'': embryonic day 12.5 (more )
Note: Double labeled: green - Sox10; red - Myo6 (assay MGI:6438107)
Structure Level Pattern Image Note
TS20: vestibular component epithelium Present S2B' , S2B'' , S2B Expression is seen in the vestibule, including in some (but not all) presumptive hair cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory