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Gene Expression Data
Assay Details
Assay
Reference: J:149463 Lania G, et al., Early thyroid development requires a Tbx1-Fgf8 pathway. Dev Biol. 2009 Apr 1;328(1):109-17
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6423603
Gene symbol: Tg
Gene name: thyroglobulin
Antibody: Anti-Tg
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 1c: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: thyroid gland follicle Present 1c
Specimen 1c': embryonic day 18.5; Tbx1tm1Bld/Tbx1tm1Bld (more )
Structure Level Pattern Image Note
TS26: thyroid gland follicle Present 1c' Expression is normal.
Specimen 3c: embryonic day 18.5; Mesp1tm2(cre)Ysa/Mesp1+, Tbx1tm3.1Bld/Tbx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: thyroid gland Present 3c
Specimen 3c': embryonic day 18.5; Mesp1tm2(cre)Ysa/Mesp1+, Tbx1tm3Bld/Tbx1tm3.1Bld (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: thyroid gland Present 3c' Authors report strong reduction in organ size.
Specimen 4d: embryonic day 18.5; Fgf8tm1.3Mrt/Fgf8+, Tbx1tm6(cre)Bld/Tbx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: thyroid gland Present 4d
Specimen 4d': embryonic day 18.5; Fgf8tm1Mrc/Fgf8tm1.3Mrt, Tbx1tm6(cre)Bld/Tbx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: thyroid gland Present 4d' Thyroid gland is smaller than controls.
Specimen S5a: embryonic day 18.5; Tbx1tm3Bld/Tbx1+, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: thyroid gland Present S5a
Specimen S5b: embryonic day 18.5; Tbx1tm1Bld/Tbx1tm3Bld, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: thyroid gland Present S5b Authors report thyroid was of normal size.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory