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Gene Expression Data
Assay Details
Assay
Reference: J:93163 Boulet AM, et al., The roles of Fgf4 and Fgf8 in limb bud initiation and outgrowth. Dev Biol. 2004 Sep 15;273(2):361-72
Assay type: RNA in situ
MGI Accession ID: MGI:6423489
Gene symbol: Fgf10
Gene name: fibroblast growth factor 10
Probe: Fgf10 probe49
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud Present 1H
Specimen 1I: embryonic day 9.5; Fgf8tm2Mrc/Fgf8+, Tg(Lefty2-cre)21bHmd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: forelimb bud Present 1I Expression pattern indistinguishable from controls.
Specimen 6A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud Present 6A
Specimen 6B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 6B
TS17: hindlimb bud Present 6B
Specimen 6C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 6C
TS19: hindlimb bud Present 6C
Specimen 6D: embryonic day 10.5; Fgf4tm1Mrc/Fgf4tm1Mrc, Fgf8tm2Mrc/Fgf8tm2Mrc, Tg(Rarb-cre)1Mrc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Weak Regionally restricted 6D Expression in most distal portion of forelimb bud, at lower level than in controls.
Specimen E11 forelimb bud not shown: embryonic day 11.0; Fgf4tm1Mrc/Fgf4tm1Mrc, Fgf8tm2Mrc/Fgf8tm2Mrc, Tg(Rarb-cre)1Mrc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS18: forelimb bud Trace Regionally restricted Expression in distal-most tipe of limb bud, greatly reduced compared fo controls.
Specimen 6E: embryonic day 11.5; Fgf4tm1Mrc/Fgf4tm1Mrc, Fgf8tm2Mrc/Fgf8tm2Mrc, Tg(Rarb-cre)1Mrc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Trace Regionally restricted 6E Expression in distal-most tipe of limb bud, greatly reduced compared fo controls.
TS19: hindlimb bud Present 6E
Specimen 6F: embryonic day 9.5; Fgf4tm1Mrc/Fgf4tm1Mrc, Fgf8tm2Mrc/Fgf8tm2Mrc, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: forelimb bud Weak Regionally restricted 6F Expression only slightly reduced compared to controls.
Specimen 6G: embryonic day 10.5; Fgf4tm1Mrc/Fgf4tm1Mrc, Fgf8tm2Mrc/Fgf8tm2Mrc, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Trace Regionally restricted 6G Expression in distal-most tip of limb bud, greatly reduced compared fo controls.
TS17: hindlimb bud Present 6G
Specimen E11 hindlimb bud not shown: embryonic day 11.0; Fgf4tm1Mrc/Fgf4tm1Mrc, Fgf8tm2Mrc/Fgf8tm2Mrc, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS18: hindlimb bud Absent Expression not detectable over background.
Specimen 6H: embryonic day 11.5; Fgf4tm1Mrc/Fgf4tm1Mrc, Fgf8tm2Mrc/Fgf8tm2Mrc, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 6H
TS19: hindlimb bud Absent 6H Expression not detectable over background.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory