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Gene Expression Data
Assay Details
Assay
Reference: J:150759 Lallemand Y, et al., Msx genes are important apoptosis effectors downstream of the Shh/Gli3 pathway in the limb. Dev Biol. 2009 Jul 15;331(2):189-98
Assay type: RNA in situ
MGI Accession ID: MGI:6404399
Gene symbol: Hoxd11
Gene name: homeobox D11
Results
Specimen 5D Forelimb Control: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 5D FL Control

Specimen 5D Forelimb Shh-/-: embryonic day 11.5; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS19: forelimb bud Ambiguous 5D FL Shh-/- Expression downregulated.

Specimen 5D Forelimb Shh-/-Msx1-/-Msx2+/-: embryonic day 11.5; Msx1tm1Bero/Msx1tm1Bero, Msx2tm1Bero/Msx2+, Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS19: forelimb bud Ambiguous 5D FL Shh-/- Msx1-/- Msx2+/-

Specimen 5D Forelimb Shh-/-Msx1-/-Msx2-/-: embryonic day 11.5; Msx1tm1Bero/Msx1tm1Bero, Msx2tm1Bero/Msx2tm1Bero, Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS19: forelimb bud Ambiguous 5D FL Shh-/- Msx1-/- Msx2-/- Expression not recovered.

Specimen 5D Hindlimb Control: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present 5D HL Control

Specimen 5D Hindlimb Shh-/-: embryonic day 11.5; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Ambiguous 5D HL Shh-/- Expression downregulated.

Specimen 5D Hindlimb Shh-/-Msx1-/-Msx2+/-: embryonic day 11.5; Msx1tm1Bero/Msx1tm1Bero, Msx2tm1Bero/Msx2+, Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Ambiguous 5D HL Shh-/- Msx1-/- Msx2+/-

Specimen 5D Hindlimb Shh-/-Msx1-/-Msx2-/-: embryonic day 11.5; Msx1tm1Bero/Msx1tm1Bero, Msx2tm1Bero/Msx2tm1Bero, Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Ambiguous 5D HL Shh-/- Msx1-/- Msx2-/- Expression not recovered.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory