About   Help   FAQ
Msx1tm1Bero
Targeted Allele Detail
Summary
Symbol: Msx1tm1Bero
Name: msh homeobox 1; targeted mutation 1, Benoit Robert
MGI ID: MGI:1933766
Synonyms: Msx1-, Msx1nlacZ, Msx1-nlacZ
Gene: Msx1  Location: Chr5:37977835-37981929 bp, - strand  Genetic Position: Chr5, 20.21 cM
Alliance: Msx1tm1Bero page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:42035
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprt1b-m3
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsAn n-lacZ reporter gene was inserted in-frame into the sequence encoding the third helix of the homeodomain. A fusion protein of the first 43 amino acids and beta-galactosidase is expressed from this allele. (J:42035)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 282 assay results
In Structures Affected by this Mutation: 19 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Msx1 Mutation:  18 strains or lines available
References
Original:  J:42035 Houzelstein D, et al., Insertional mutation of the mouse Msx1 homeobox gene by an nlacZ reporter gene. Mech Dev. 1997 Jul;65(1-2):123-33
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory