About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:272619 Aydogdu N, et al., TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827
Assay type: RNA in situ
MGI Accession ID: MGI:6385389
Gene symbol: Tbx2
Gene name: T-box 2
Probe: Tbx2 probe14
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A E12.5: embryonic day 12.5 (more )
Note: proximal (kidney) level
Structure Level Pattern Image Note
TS20: epithelial layer of ureter Strong 1A E12.5 Tbx2
TS20: ureteral mesenchyme subepithelial layer Present 1A E12.5 Tbx2
Specimen 1A E14.5: embryonic day 14.5 (more )
Note: proximal (kidney) level
Structure Level Pattern Image Note
TS22: urothelium of ureter Strong 1A E14.5 Tbx2
TS22: ureteral mesenchyme subepithelial layer Present 1A E14.5 Tbx2
Specimen 1A E16.5: embryonic day 16.5 (more )
Note: proximal (kidney) level
Structure Level Pattern Image Note
TS24: urothelium of ureter Strong 1A E16.5 Tbx2
TS24: ureteral mesenchyme subepithelial layer Present 1A E16.5 Tbx2
Specimen 1A E18.5: embryonic day 18.5 (more )
Note: proximal (kidney) level
Structure Level Pattern Image Note
TS26: urothelium of ureter Strong 1A E18.5 Tbx2
Specimen 1C control: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: epithelial layer of ureter Strong 1C control Tbx2
TS20: ureteral mesenchyme subepithelial layer Present 1C control Tbx2
Specimen 1C Tbx18cre/+;Ctnnb1fl/fl: embryonic day 12.5; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: epithelial layer of ureter Strong 1C Tbx18cre/+;Ctnnb1fl/fl Tbx2
TS20: ureteral mesenchyme subepithelial layer Absent 1C Tbx18cre/+;Ctnnb1fl/fl Tbx2
Specimen 1C Tbx18cre/+;Ctnnb1(ex3)fl/+: embryonic day 12.5; Ctnnb1tm1Mmt/Ctnnb1tm1Mmt, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: epithelial layer of ureter Strong 1C Tbx18cre/+;Ctnnb1(ex3)fl/+ Tbx2
TS20: ureteral mesenchyme Present 1C Tbx18cre/+;Ctnnb1(ex3)fl/+ Tbx2 Misexpression of a stabilized version of Ctnnb1 in the entire ureteric mesenchyme resulted in increased and expanded expression of Tbx2.
Specimen 1C Tbx18cre/+;Smofl/fl: embryonic day 12.5; Smotm2Amc/Smotm2Amc, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: epithelial layer of ureter Strong 1C Tbx18cre/+;Smofl/fl Tbx2
TS20: ureteral mesenchyme subepithelial layer Present 1C Tbx18cre/+;Smofl/fl Tbx2 Loss of Smo had no effect on Tbx2 expression in the ureteric mesenchyme at E12.5.
Specimen S2A E12.5: embryonic day 12.5 (more )
Note: distal (close to the bladder) level
Structure Level Pattern Image Note
TS20: epithelial layer of ureter Strong S2A E12.5 Tbx2
TS20: ureteral mesenchyme subepithelial layer Weak S2A E12.5 Tbx2
Specimen S2A E13.5: embryonic day 13.5 (more )
Note: distal (close to the bladder) level
Structure Level Pattern Image Note
TS21: urothelium of ureter Strong S2A E13.5 Tbx2
TS21: ureteral mesenchyme subepithelial layer Weak S2A E13.5 Tbx2
Specimen S2A E14.5: embryonic day 14.5 (more )
Note: distal (close to the bladder) level
Structure Level Pattern Image Note
TS22: urothelium of ureter Strong S2A E14.5 Tbx2
TS22: ureteral mesenchyme subepithelial layer Weak S2A E14.5 Tbx2
Specimen S2A E16.5: embryonic day 16.5 (more )
Note: distal (close to the bladder) level
Structure Level Pattern Image Note
TS24: urothelium of ureter Strong S2A E16.5 Tbx2
TS24: ureteral mesenchyme subepithelial layer Weak S2A E16.5 Tbx2
Specimen S2A E18.5: embryonic day 18.5 (more )
Note: distal (close to the bladder) level
Structure Level Pattern Image Note
TS26: urothelium of ureter Strong S2A E18.5 Tbx2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory