Gene Expression Image Detail

Reference

Figure

ID

J:272619 Aydogdu N, et al., Development. 2018 Nov 26;145(23):dev171827

1

MGI:6385208

Image

Caption

(A,B) RNA in situ hybridization (A) and immunofluorescence analysis (B) on transverse sections through the posterior trunk region of wildtype embryos at the proximal (kidney) level of the ureter. Arrows point to the mesenchymal expression domain in E12.5 ureters. Nuclei (blue) are counterstained with DAPI in B. (C) Comparative RNA in situ hybridization analysis on transverse sections through the posterior trunk region of E12.5 wild-type embryos, of embryos with loss of Ctnnb1-dependent WNT signaling (Tbx18^cre/+;Ctnnb1^fl/fl), with gain of Ctnnb1-dependent WNT signaling (Tbx18^cre/+;Ctnnb1^(ex3)fl/+) and loss of SHH/SMO signaling (Tbx18^cre/+;Smo^fl/fl) in the UM. k, kidney; ue, ureteric epithelium; um, ureteric mesenchyme.

Copyright

This image is from Aydogdu N, Development 2018 Nov 26;145(23): and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A E12.5 Tbx2	MGI:6385389 (Tbx2)
A E12.5 Tbx3	MGI:6385390 (Tbx3)
A E14.5 Tbx2	MGI:6385389 (Tbx2)
A E14.5 Tbx3	MGI:6385390 (Tbx3)
A E16.5 Tbx2	MGI:6385389 (Tbx2)
A E16.5 Tbx3	MGI:6385390 (Tbx3)
A E18.5 Tbx2	MGI:6385389 (Tbx2)
A E18.5 Tbx3	MGI:6385390 (Tbx3)
B E12.5 TBX2	MGI:6385391 (Tbx2)
B E12.5 TBX3	MGI:6385392 (Tbx3)
B E14.5 TBX2	MGI:6385391 (Tbx2)
B E14.5 TBX3	MGI:6385392 (Tbx3)
B E16.5 TBX2	MGI:6385391 (Tbx2)
B E16.5 TBX3	MGI:6385392 (Tbx3)
B E18.5 TBX2	MGI:6385391 (Tbx2)
B E18.5 TBX3	MGI:6385392 (Tbx3)
C control Tbx2	MGI:6385389 (Tbx2)
C control Tbx3	MGI:6385390 (Tbx3)
C Tbx18^cre/+;Ctnnb1^fl/fl Tbx2	MGI:6385389 (Tbx2)
C Tbx18^cre/+;Ctnnb1^fl/fl Tbx3	MGI:6385390 (Tbx3)
C Tbx18^cre/+;Ctnnb1^(ex3)fl/+ Tbx2	MGI:6385389 (Tbx2)
C Tbx18^cre/+;Ctnnb1^(ex3)fl/+ Tbx3	MGI:6385390 (Tbx3)
C Tbx18^cre/+;Smo^fl/fl Tbx2	MGI:6385389 (Tbx2)
C Tbx18^cre/+;Smo^fl/fl Tbx3	MGI:6385390 (Tbx3)