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Gene Expression Data
Assay Details
Assay
Reference: J:276416 Zhuang M, et al., The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression. Nucleic Acids Res. 2019 May 21;47(9):4765-4777
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6361507
Gene symbol: Ythdf1
Gene name: YTH N6-methyladenosine RNA binding protein 1
Antibody: anti-YTHDF1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5B fl/fl: embryonic day 11.5; Ythdf1tm1.1Sjj/Ythdf1tm1.1Sjj (more )
Structure Level Pattern Image Note
TS19: future spinal cord Present Widespread 5B left

Specimen 5B cKO: embryonic day 11.5; Ythdf1tm1.1Sjj/Ythdf1tm1.1Sjj, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 5B right Depletion of protein in the dorsal spinal cord of the mutants.

Specimen 5C left: embryonic day 11.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Atoh1-cre)1Bfri/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: future spinal cord Present 5C left

Specimen 5C right: embryonic day 11.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Atoh1-cre)1Bfri/0, Ythdf1tm1.1Sjj/Ythdf1tm1.1Sjj (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 5C right Specific ablation of the expression from Atoh1-Cre+ commissural neurons.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory