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Gene Expression Data
Assay Details
Assay
Reference: J:258043 Wang Y, et al., N(6)-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications. Nat Neurosci. 2018 Feb;21(2):195-206
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6358350
Gene symbol: Mettl14
Gene name: methyltransferase 14, N6-adenosine-methyltransferase subunit
Antibody: anti-Mettl14 (HPA038002)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1e Mettl14f/f: embryonic day 17.5; Mettl14tm1.1Czhao/Mettl14tm1.1Czhao (more )
Note: Double labeled: green - Mettl14; red - Pax6 (assay MGI:6358383).
Structure Level Pattern Image Note
TS25: cerebral cortex Present 1e merge Mettl14f/f , 1e Mettl14 Mettl14f/f
Specimen 1e Mettl14f/f;Nestin-cre: embryonic day 17.5; Mettl14tm1.1Czhao/Mettl14tm1.1Czhao, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: green - Mettl14; red - Pax6 (assay MGI:6358383).
Structure Level Pattern Image Note
TS25: cerebral cortex Absent 1e Mettl14 Mettl14f/f;Nestin-cre , 1e merge Mettl14f/f;Nestin-cre
Specimen 1e Mettl14f/+;Nestin-cre: embryonic day 17.5; Mettl14tm1.1Czhao/Mettl14+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: green - Mettl14; red - Pax6 (assay MGI:6358383).
Structure Level Pattern Image Note
TS25: cerebral cortex Present 1e Mettl14 Mettl14f/+;Nestin-cre , 1e merge Mettl14f/+;Nestin-cre
Specimen 1f E13.5 Mettl14f/f: embryonic day 13.5; Mettl14tm1.1Czhao/Mettl14tm1.1Czhao (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present 1f E13.5 Mettl14f/f
Specimen 1f E13.5 Mettl14f/f;Nestin-cre: embryonic day 13.5; Mettl14tm1.1Czhao/Mettl14tm1.1Czhao, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: cerebral cortex Trace 1f E13.5 Mettl14f/f;Nestin-cre
Specimen 1f E13.5 Mettl14f/+;Nestin-cre: embryonic day 13.5; Mettl14tm1.1Czhao/Mettl14+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: cerebral cortex Present 1f E13.5 Mettl14f/+;Nestin-cre
Specimen 1f E15.5 Mettl14f/f: embryonic day 15.5; Mettl14tm1.1Czhao/Mettl14tm1.1Czhao (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present 1f E15.5 Mettl14f/f
Specimen 1f E15.5 Mettl14f/f;Nestin-cre: embryonic day 15.5; Mettl14tm1.1Czhao/Mettl14tm1.1Czhao, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cerebral cortex Absent 1f E15.5 Mettl14f/f;Nestin-cre
Specimen 1f E15.5 Mettl14f/+;Nestin-cre: embryonic day 15.5; Mettl14tm1.1Czhao/Mettl14+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cerebral cortex Present 1f E15.5 Mettl14f/+;Nestin-cre
Specimen 1f E17.5 Mettl14f/f: embryonic day 17.5; Mettl14tm1.2Czhao/Mettl14tm1.2Czhao (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present 1f E17.5 Mettl14f/f
Specimen 1f E17.5 Mettl14f/f;Nestin-cre: embryonic day 17.5; Mettl14tm1.1Czhao/Mettl14tm1.1Czhao, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: cerebral cortex Absent 1f E17.5 Mettl14f/f;Nestin-cre
Specimen 1f E17.5 Mettl14f/+;Nestin-cre: embryonic day 17.5; Mettl14tm1.1Czhao/Mettl14+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: cerebral cortex Present 1f E17.5 Mettl14f/+;Nestin-cre
Specimen 1f P0 Mettl14f/f: postnatal day 0; Mettl14tm1.1Czhao/Mettl14tm1.1Czhao (more )
Structure Level Pattern Image Note
TS27: cerebral cortex Present 1f P0 Mettl14f/f
Specimen 1f P0 Mettl14f/f;Nestin-cre: postnatal day 0; Mettl14tm1.1Czhao/Mettl14tm1.1Czhao, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cerebral cortex Absent 1f P0 Mettl14f/f;Nestin-cre
Specimen 1f P0 Mettl14f/+;Nestin-cre: postnatal day 0; Mettl14tm1.1Czhao/Mettl14+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cerebral cortex Present 1f P0 Mettl14f/+;Nestin-cre
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory