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Gene Expression Data
Assay Details
Assay
Reference: J:68156 Casas C, et al., Dscr1, a novel endogenous inhibitor of calcineurin signaling, is expressed in the primitive ventricle of the heart and during neurogenesis. Mech Dev. 2001 Mar;101(1-2):289-92
Assay type: RNA in situ
MGI Accession ID: MGI:5461518
Gene symbol: Rcan1
Gene name: regulator of calcineurin 1
Probe: Dscr1 cDNA1
Probe preparation: Antisense RNA
Results
Specimen 2A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: bulbus cordis Present 2A
TS15: primitive ventricle Present 2A
TS15: heart Present Regionally restricted 2A Expression was detected in the truncus arteriosus.
TS15: central nervous system Weak 2A
Specimen 2B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: bulbus cordis Present 2B
TS17: primitive ventricle Present 2B
TS17: heart Present Regionally restricted 2B Expression was detected in the truncus arteriosus.
TS17: central nervous system Weak 2B
Specimen 2C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain basal plate Present 2C
TS19: telencephalon Present 2C
TS19: midbrain Present Regionally restricted 2C Expression was detected in the pretectum.
TS19: diencephalon Present Regionally restricted 2C Expression was detected in caudal hypothalamus.
Specimen 2D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2D Expression was detected in rhombomere 4 with rostral and caudal expansion into rhombomeres 3 and 5.
TS19: future spinal cord Present 2D
Specimen 2E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Widespread 2E
TS20: hindbrain basal plate Present 2E
TS20: spinal cord Present 2E
TS20: telencephalon Present 2E
TS20: hypothalamus Present Regionally restricted 2E Expression was detected in caudal hypothalamus.
Specimen 3A: embryonic day 14.5 (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 3A
TS22: corpus striatum Present 3A
TS22: cortical plate Present 3A
TS22: hippocampus Present 3A
TS22: hypothalamus Present 3A
TS22: pretectum Present 3A
Specimen 3B: embryonic day 16.5 (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present 3B
TS24: corpus striatum Present 3B
TS24: cortical plate Present 3B
TS24: hippocampus Present 3B
TS24: hypothalamus Present 3B
TS24: pretectum Present 3B
Specimen 3C: postnatal day 0 (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS27: amygdala Present 3C
TS27: cerebral cortex Present 3C
TS27: corpus striatum Present 3C
TS27: habenula Present 3C
TS27: hippocampus Present 3C
TS27: hypothalamus Present 3C
Specimen 3D: postnatal day 10 (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS28: amygdala Present 3D
TS28: cerebral cortex Present 3D
TS28: dentate gyrus granule cell layer Present 3D
TS28: habenula Present 3D
TS28: hippocampus granule cell layer Present 3D
TS28: hippocampus pyramidal cell layer Present 3D
TS28: hypothalamus Present 3D
Specimen 3E: postnatal adult (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS28: amygdala Present 3E
TS28: cerebral cortex Present 3E
TS28: dentate gyrus granule cell layer Present 3E
TS28: habenula Present 3E
TS28: hippocampus granule cell layer Present 3E
TS28: hippocampus pyramidal cell layer Present 3E
TS28: hypothalamus Present 3E
Specimen 3F: postnatal day 0 (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS27: main olfactory bulb mitral cell layer Present 3F
Specimen 3G: postnatal adult (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS28: main olfactory bulb granule cell layer Present 3G
TS28: main olfactory bulb mitral cell layer Present 3G
TS28: main olfactory bulb glomerular layer Present 3G Expression was detected in the periglomerular cells in the adult.
Specimen 3H: postnatal day 10 (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS28: cortical layer II Present 3H
TS28: cortical layer III Present 3H
TS28: cortical layer V Present 3H
Specimen 3I: postnatal adult (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS28: cortical layer II Ambiguous 3I There was a marked decrease in expression in the adult compared to postnatal day 10.
TS28: cortical layer III Ambiguous 3I There was a marked decrease in expression in the adult compared to postnatal day 10.
TS28: cortical layer V Ambiguous 3I There was a marked decrease in expression in the adult compared to postnatal day 10.
Specimen 3J: postnatal day 0 (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS27: corpus striatum Present 3J
TS27: telencephalon septum Present 3J
Specimen 3K: postnatal adult (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS28: corpus striatum Ambiguous 3K There was a marked decrease in expression in the adult compared to postnatal day 0.
TS28: telencephalon septum Ambiguous 3K There was a marked decrease in expression in the adult compared to postnatal day 0.
Specimen 3L: postnatal day 10 (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS28: inferior colliculus Present 3L
TS28: mammillary body Present 3L
TS28: substantia nigra Present 3L
TS28: superior colliculus Present 3L
Specimen 3M: postnatal adult (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS28: inferior colliculus Ambiguous 3M There was a marked decrease in expression in the adult compared to postnatal day 10.
TS28: mammillary body Ambiguous 3M There was a marked decrease in expression in the adult compared to postnatal day 10.
TS28: substantia nigra Ambiguous 3M There was a marked decrease in expression in the adult compared to postnatal day 10.
TS28: superior colliculus Ambiguous 3M There was a marked decrease in expression in the adult compared to postnatal day 10.
Specimen 3N: postnatal day 10 (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 3N
Specimen 3O: postnatal adult (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Ambiguous 3O There was a marked decrease in expression in the adult compared to postnatal day 10.
Specimen 3P: postnatal adult (more )
Note: Section was free-floating. Double labeled: purple - Rcan1; brown - Gfap (assay MGI:5461739).
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 3P Expression was detected in neurons and not in astrocytes.
Specimen not shown: postnatal (more )
Note: Section was free-floating.
Structure Level Pattern Image Note
TS28: dorsal raphe nucleus Present
TS28: locus coeruleus Present
TS28: solitary tract nucleus Present
TS28: metencephalon Present Regionally restricted Expression was detected in the olivary nuclei.
TS28: nervous system Present Regionally restricted Expression was detected in the sensory and motor nuclei of the cranial nerves.
TS28: spinal cord Present Scattered
Specimen 4B: postnatal adult; Ts(1716)65Dn/0 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 4B No differences in expression pattern were noted compared to control littermates.
TS28: piriform cortex Present 4B No differences in expression pattern were noted compared to control littermates.
TS28: telencephalon septum Present 4B No differences in expression pattern were noted compared to control littermates.
TS28: corpus striatum Absent 4B No differences in expression pattern were noted compared to control littermates.
Specimen 4C: postnatal adult; Ts(1716)65Dn/0 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 4C No differences in expression pattern were noted compared to control littermates.
Specimen 4D: postnatal adult; Ts(1716)65Dn/0 (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 4D No differences in expression pattern were noted compared to control littermates.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory