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Cyp2c69 Gene Detail
Summary
  • Symbol
    Cyp2c69
  • Name
    cytochrome P450, family 2, subfamily c, polypeptide 69
  • Synonyms
    AI098658
  • Feature Type
    protein coding gene
  • IDs
    MGI:3721049
    NCBI Gene: 100043108
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:39831258-39875243 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 34.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    169 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3721049
 protein coding gene Chr19:39831104-39875243 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025105
 protein coding gene Chr19:38717079-38885432 (-)
A/J MGP_AJ_G0025082
 protein coding gene Chr19:36986609-37030543 (-)
AKR/J MGP_AKRJ_G0025050
 protein coding gene Chr19:38236202-38303049 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0024837
 protein coding gene Chr19:38335960-38392509 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025521
 protein coding gene Chr19:40025707-40085790 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0024816
 protein coding gene Chr19:42015036-42066410 (-)
DBA/2J MGP_DBA2J_G0024948
 protein coding gene Chr19:36934258-36982523 (-)
FVB/NJ MGP_FVBNJ_G0024908
 protein coding gene Chr19:36580876-36641298 (-)
LP/J MGP_LPJ_G0025034
 protein coding gene Chr19:39036662-39092316 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024939
 protein coding gene Chr19:41386993-41438560 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025577
 protein coding gene Chr19:38423799-38479333 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0024371
 protein coding gene Chr19:38281888-38324794 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000092008 Ensembl Gene Model | MGI Sequence Detail 43986 C57BL/6J ±  kb
transcript ENSMUST00000168838 Ensembl | MGI Sequence Detail 1646 Not Applicable  
polypeptide ENSMUSP00000132832 Ensembl | MGI Sequence Detail 491 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
    IPR036396 Cytochrome P450 superfamily
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11
Other
Accession IDs
less
MGI:3612289
References
more
  • Summaries
    All 15
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:241121 Scheer N, et al., Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines. Mol Pharmacol. 2012 Dec;82(6):1022-9
  • Latest
    J:341617 Zhang J, et al., CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid. FASEB J. 2023 Jul;37(7):e23009
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory