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Gm5414 Gene Detail
Summary
  • Symbol
    Gm5414
  • Name
    predicted gene 5414
  • Feature Type
    protein coding gene
  • IDs
    MGI:3646939
    NCBI Gene: 406223
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:101532463-101536623 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.94 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    48 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646939
 protein coding gene Chr15:101532463-101536687 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022381
 protein coding gene Chr15:103724759-103734195 (-)
A/J MGP_AJ_G0022343
 protein coding gene Chr15:99607933-99623589 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0022347
 protein coding gene Chr15:99719116-99725162 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0022795
 protein coding gene Chr15:107593657-107599508 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0021641
 protein coding gene Chr15:103592851-103597197 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0022283
 protein coding gene Chr15:103886765-103893941 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022213
 protein coding gene Chr15:114982404-114987980 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022809
 protein coding gene Chr15:102696040-102700116 (-)
PWK/PhJ MGP_PWKPhJ_G0021380
 protein coding gene Chr15:99120482-99125138 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021213
 protein coding gene Chr15:102586297-102590713 (-)
WSB/EiJ MGP_WSBEiJ_G0021691
 protein coding gene Chr15:103336351-103341147 (-)



Homology
more
  • Human Ortholog
    KRT6A, keratin 6A
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT6A, keratin 6A
  • Synonyms
    CK6A, CK6C, CK-6C, CK6D, CK-6E, K6A, K6C, K6D, KRT6C, KRT6D, PC3
  • Links
    NCBI Gene ID: 3853
    neXtProt AC: NX_P02538
    UniProt: P02538

  • Chr Location
    12q13.13; chr12:52487176-52493257 (-)  GRCh38
  • Human Ortholog
    KRT6B, keratin 6B
  • Synonyms
    CK6B, CK-6B, K6B, KRTL1, PC2, PC4
  • Links
    NCBI Gene ID: 3854
    neXtProt AC: NX_P04259
    UniProt: P04259

  • Chr Location
    12q13.13; chr12:52446651-52452146 (-)  GRCh38
  • Human Ortholog
    KRT6C, keratin 6C
  • Synonyms
    K6E, KRT6E, PPKNEFD
  • Links
    NCBI Gene ID: 286887
    neXtProt AC: NX_P48668
    UniProt: P48668

  • Chr Location
    12q13.13; chr12:52468516-52473805 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human KRT6A,KRT6B,KRT6C associations

Human Disease Mouse Models
      
IDs
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    4 involving Gm5414
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    23 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064232 Ensembl Gene Model | MGI Sequence Detail 4161 C57BL/6J ±  kb
transcript ENSMUST00000062879 Ensembl | MGI Sequence Detail 1659 Not Applicable  
polypeptide ENSMUSP00000059101 Ensembl | MGI Sequence Detail 552 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR018039 Intermediate filament protein, conserved site
    IPR039008 Intermediate filament, rod domain
    IPR003054 Keratin, type II
    IPR032444 Keratin type II head
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 37
    Diseases 1
    Gene Ontology 1
    Phenotypes 27
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory