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Kir3dl2 Gene Detail
Summary
  • Symbol
    Kir3dl2
  • Name
    killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
  • Synonyms
    Kirl2, LOC245615
  • Feature Type
    protein coding gene
  • IDs
    MGI:3612791
    NCBI Gene: 245615
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    ChrX:135348856-135444805 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 58.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    261 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3612791
 protein coding gene ChrX:135348676-135444826 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036099
 protein coding gene ChrX:133817603-133924794 (+)
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0036068
 protein coding gene ChrX:131609722-131630072 (-)
C3H/HeJ MGP_C3HHeJ_G0035779
 protein coding gene ChrX:133807862-133942767 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036593
 protein coding gene ChrX:137775584-137812951 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0035754
 protein coding gene ChrX:141901874-142009177 (-)
DBA/2J MGP_DBA2J_G0035910
 protein coding gene ChrX:132557610-132579559 (-)
FVB/NJ MGP_FVBNJ_G0035845
 protein coding gene ChrX:131648148-131818375 (+)
LP/J MGP_LPJ_G0036006
 protein coding gene ChrX:134741336-134764980 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0035201
 protein coding gene ChrX:131537175-131633415 (-)



Homology
more
  • Human Ortholog
    KIR2DL1, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
  • Vertebrate Orthologs
    18
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KIR2DL1, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
  • Synonyms
    CD158A, KIR221, KIR2DL3, KIR-K64, NKAT, NKAT1, NKAT-1, p58.1
  • Links
    NCBI Gene ID: 3802
    neXtProt AC: NX_P43626
    UniProt: P43626

  • Chr Location
    19q13.42; chr19:54769793-54784322 (+)  GRCh38
  • Human Ortholog
    KIR2DL2, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2
  • Synonyms
    CD158b, CD158B1, NKAT6, NKAT-6, p58.2
  • Links
    NCBI Gene ID: 3803
    neXtProt AC: NX_P43627
    UniProt: P43627

  • Chr Location
    19q13.4
  • Human Ortholog
    KIR2DL3, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
  • Synonyms
    CD158b, CD158B2, GL183, KIR-023GB, KIR2DL, KIR2DS5, KIRCL23, KIR-K7b, KIR-K7c, NKAT, NKAT2, NKAT2A, NKAT2B, p58
  • Links
    NCBI Gene ID: 3804
    neXtProt AC: NX_P43628
    UniProt: P43628

  • Chr Location
    19q13.42; chr19:54738513-54753052 (+)  GRCh38
  • Human Ortholog
    KIR2DL4, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
  • Synonyms
    CD158D, G9P, KIR103, KIR103AS, KIR-103AS, KIR-2DL4
  • Links
    NCBI Gene ID: 3805
    neXtProt AC: NX_Q99706
    UniProt: Q99706

  • Chr Location
    19q13.42; chr19:54803610-54814517 (+)  GRCh38
  • Human Ortholog
    KIR2DL5A, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A
  • Synonyms
    CD158F, KIR2DL5, KIR2DL5.1, KIR2DL5.3
  • Links
    NCBI Gene ID: 57292
    neXtProt AC: NX_Q8N109
    UniProt: Q8N109

  • Chr Location
    19p13.3
  • Human Ortholog
    KIR2DL5B, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5B
  • Synonyms
    KIR2DL5, KIR2DL5.2, KIR2DLX
  • Links
    NCBI Gene ID: 553128
    neXtProt AC: NX_Q8NHK3
    UniProt: Q8NHK3

  • Chr Location
    19p13.3
  • Human Ortholog
    KIR2DP1, killer cell immunoglobulin like receptor, two Ig domains pseudogene 1
  • Synonyms
    KIR15, KIR2DL6, KIRY, KIRZ
  • Links
    NCBI Gene ID: 554300

  • Chr Location
    19q13.42; chr19:54754756-54767881 (+)  GRCh38
  • Human Ortholog
    KIR2DS1, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1
  • Synonyms
    CD158a, CD158H, p50.1
  • Links
    NCBI Gene ID: 3806
    neXtProt AC: NX_Q14954
    UniProt: Q14954

  • Chr Location
    19q13.4
  • Human Ortholog
    KIR2DS2, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2
  • Synonyms
    183ActI, CD158b, CD158J, cl-49, KIR2DL1, KIR-2DS2, NKAT5, NKAT-5
  • Links
    NCBI Gene ID: 100132285
    neXtProt AC: NX_P43631
    UniProt: P43631

  • Chr Location
    19
  • Human Ortholog
    KIR2DS3, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 3
  • Synonyms
    NKAT7
  • Links
    NCBI Gene ID: 3808
    neXtProt AC: NX_Q14952
    UniProt: Q14952

  • Chr Location
    19q13.4
  • Human Ortholog
    KIR2DS4, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4
  • Synonyms
    CD158I, KIR1D, KIR-2DS4, KIR412, KKA3, NKAT8, NKAT-8
  • Links
    NCBI Gene ID: 3809
    neXtProt AC: NX_P43632
    UniProt: P43632

  • Chr Location
    19q13.42; chr19:54832676-54848575 (+)  GRCh38
  • Human Ortholog
    KIR2DS5, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5
  • Synonyms
    CD158G, NKAT9
  • Links
    NCBI Gene ID: 3810
    neXtProt AC: NX_Q14953
    UniProt: Q14953

  • Chr Location
    19q13.4
  • Human Ortholog
    KIR3DL1, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
  • Synonyms
    CD158E1, KIR, KIR2DL5B, KIR3DL1/S1, NKAT3, NKAT-3, NKB1, NKB1B
  • Links
    NCBI Gene ID: 3811
    neXtProt AC: NX_P43629
    UniProt: P43629

  • Chr Location
    19q13.42; chr19:54816468-54830778 (+)  GRCh38
  • Human Ortholog
    KIR3DL2, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2
  • Synonyms
    3DL2, CD158K, KIR-3DL2, NKAT4, NKAT-4, NKAT4B, p140
  • Links
    NCBI Gene ID: 3812
    neXtProt AC: NX_P43630
    UniProt: P43630

  • Chr Location
    19q13.42; chr19:54850443-54867207 (+)  GRCh38
  • Human Ortholog
    KIR3DL3, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
  • Synonyms
    CD158Z, KIR2DL5B, KIR3DL7, KIR44, KIRC1
  • Links
    NCBI Gene ID: 115653
    UniProt: Q8N743

  • Chr Location
    19q13.42; chr19:54724442-54736632 (+)  GRCh38
  • Human Ortholog
    KIR3DP1, killer cell immunoglobulin like receptor, three Ig domains pseudogene 1
  • Synonyms
    CD158c, KIR2DS6, KIR3DS2P, KIR48, KIRX
  • Links
    NCBI Gene ID: 548594

  • Chr Location
    chr19:54786355-54790418 (+)  GRCh38
  • Human Ortholog
    KIR3DS1, killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1
  • Synonyms
    CD158E2, KIR-123FM, KIR-G1, NKAT10, NKAT-10
  • Links
    NCBI Gene ID: 3813
    neXtProt AC: NX_Q14943
    UniProt: Q14943

  • Chr Location
    19q13.4
Human Diseases
more
  • Diseases
    18 with human KIR2DL1,KIR2DL2,KIR3DL1,KIR3DS1 associations

Human Disease Mouse Models
      
IDs
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Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    12
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057439 Ensembl Gene Model | MGI Sequence Detail 95950 C57BL/6J ±  kb
transcript ENSMUST00000072125 Ensembl | MGI Sequence Detail 1734 Not Applicable  
polypeptide ENSMUSP00000071994 Ensembl | MGI Sequence Detail 388 Not Applicable  
For the selected sequence
Protein
Information
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Molecular
Reagents
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  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 14
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:83003 Welch AY, et al., Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X. Immunogenetics. 2003 Feb;54(11):782-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory