Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Artm1.1Chc Name: androgen receptor; targeted mutation 1.1, Chawnshang Chang MGI ID: MGI:2687199 Synonyms: AR-, ARKO, GARKO Gene: Ar  Location: ChrX:97192375-97366821 bp, + strand  Genetic Position: ChrX, 42.82 cM Alliance: Artm1.1Chc page

Immunostaining of androgen receptor and histological analysis of testes of Artm1.1Chc/Y mice Show the 3 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:81789
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The loxP flanked region including exon 2 was excised from Artm1Chc via cre mediated recombination. Exon 2 encodes the second zinc finger of the DNA-binding domain. (J:81789)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ar Mutation:	22 strains or lines available

Original:	J:81789 Yeh S, et al., Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13498-503
All:	19 reference(s)