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Zfp454 Gene Detail
Summary
  • Symbol
    Zfp454
  • Name
    zinc finger protein 454
  • Synonyms
    MGC:57560
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679253
    NCBI Gene: 237758
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:50763545-50778463 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 30.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    624 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679253
 protein coding gene Chr11:50763545-50778478 (-)
129S1/SvImJ ENSMUSG00200038486
 protein coding gene Chr11:47742341-47756117 (-)
A/J ENSMUSG00195030834
 protein coding gene Chr11:47693219-47706997 (-)
AKR/J ENSMUSG00220038418
 protein coding gene Chr11:47882105-47895881 (-)
BALB/cJ ENSMUSG00180031244
 protein coding gene Chr11:47754708-47768486 (-)
C3H/HeJ ENSMUSG00175032141
 protein coding gene Chr11:47724803-47738581 (-)
C57BL/6NJ ENSMUSG00215034807
 protein coding gene Chr11:47651630-47665408 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016297
 protein coding gene Chr11:45756728-45772383 (-)
CAST/EiJ ENSTCUG00005043275
 protein coding gene Chr11:47284857-47298588 (-)
CBA/J ENSMUSG00210027542
 protein coding gene Chr11:47580768-47594546 (-)
DBA/2J ENSMUSG00185026294
 protein coding gene Chr11:47830244-47844022 (-)
FVB/NJ ENSMUSG00205029544
 protein coding gene Chr11:47623170-47636948 (-)
JF1/MsJ ENSUMUG00000040072
 protein coding gene Chr11:48095631-48110465 (-)
LP/J ENSMUSG00230029659
 protein coding gene Chr11:48974036-48987814 (-)
NOD/ShiLtJ ENSMUSG00190037278
 protein coding gene Chr11:47843069-47856847 (-)
NZO/HlLtJ ENSMUSG00225032779
 protein coding gene Chr11:50961087-50977073 (-)
PWK/PhJ ENSLUMG00010031893
 protein coding gene Chr11:47609762-47624099 (-)
SPRET/EiJ ENSMSPG00010016346
 protein coding gene Chr11:48271048-48285785 (-)
WSB/EiJ ENSIUOG00005036062
 protein coding gene Chr11:47638313-47652091 (-)



Homology
more
  • Human Ortholog
    ZNF454, zinc finger protein 454
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF454, zinc finger protein 454
  • Links
    NCBI Gene ID: 285676
    UniProt: Q8N9F8

  • Chr Location
    5q35.3; chr5:178940827-178990028 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    651
  • Tissues
    32
  • cDNA Data
    15
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 237758 NCBI Gene Model | MGI Sequence Detail 14919 C57BL/6J ±  kb
transcript NM_172794 RefSeq | MGI Sequence Detail 2137 C57BL/6  
polypeptide NP_766382 RefSeq | MGI Sequence Detail 536 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR050589 Ikaros C2H2-type zinc-finger
    IPR001909 Krueppel-associated box
    IPR036051 Krueppel-associated box domain superfamily
    IPR050169 Krueppel C2H2-type zinc-finger
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:91257 Gray PA, et al., Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory