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Mir145a Gene Detail
Summary
  • Symbol
    Mir145a
  • Name
    microRNA 145a
  • Synonyms
    Mirn145, mmu-mir-145, mmu-mir-145a
Location &
Maps
more
  • Sequence Map
    Chr18:61780896-61780965 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 34.64 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    108 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676830
 miRNA gene Chr18:61780896-61780965 (-)
129S1/SvImJ ENSMUSG00200034594
 miRNA gene Chr18:58945977-58946046 (-)
A/J ENSMUSG00195005514
 miRNA gene Chr18:59012201-59012270 (-)
AKR/J ENSMUSG00220016820
 miRNA gene Chr18:59001418-59001487 (-)
BALB/cJ ENSMUSG00180012529
 miRNA gene Chr18:59579288-59579357 (-)
C3H/HeJ ENSMUSG00175038301
 miRNA gene Chr18:59194608-59194677 (-)
C57BL/6NJ ENSMUSG00215040416
 miRNA gene Chr18:58514548-58514617 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0007603
 miRNA gene Chr18:58450663-58450732 (-)
CAST/EiJ ENSTCUG00005028390
 miRNA gene Chr18:58215778-58215847 (-)
CBA/J ENSMUSG00210033546
 miRNA gene Chr18:59141892-59141961 (-)
DBA/2J ENSMUSG00185015828
 miRNA gene Chr18:59041856-59041925 (-)
FVB/NJ ENSMUSG00205018795
 miRNA gene Chr18:58526028-58526097 (-)
JF1/MsJ ENSUMUG00000038124
 miRNA gene Chr18:58923347-58923416 (-)
LP/J ENSMUSG00230040146
 miRNA gene Chr18:61105602-61105671 (-)
NOD/ShiLtJ ENSMUSG00190035300
 miRNA gene Chr18:58799056-58799125 (-)
NZO/HlLtJ ENSMUSG00225030901
 miRNA gene Chr18:60979329-60979398 (-)
PWK/PhJ ENSLUMG00010008745
 miRNA gene Chr18:59326325-59326394 (-)
SPRET/EiJ ENSMSPG00010018421
 miRNA gene Chr18:59563467-59563536 (-)
WSB/EiJ ENSIUOG00005009982
 miRNA gene Chr18:58671254-58671323 (-)



Homology
more
  • Human Ortholog
    MIR145, microRNA 145
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR145, microRNA 145
  • Synonyms
    miR-145, MIRN145, miRNA145
  • Links
    NCBI Gene ID: 406937

  • Chr Location
    chr5:149430646-149430733 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit vascular smooth muscle hypotrophy, decreased blood pressure, decreased heart weight, and failure to respond normally to carotide artery ligation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    784
  • Tissues
    40
  • Literature Summary
    21
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      25
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 387163 NCBI Gene Model | MGI Sequence Detail 70 C57BL/6J ±  kb
    transcript NR_029557 RefSeq | MGI Sequence Detail 70 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 9
      Primer pair 6
      Other 3
    Other Database
    Links
    less
    miRBase MI0000169
    References
    more
    • Summaries
      All 99
      Developmental Gene Expression 21
      Gene Ontology 9
      Phenotypes 9
    • Earliest
      J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
    • Latest
      J:382542 Li P, et al., Transplantation of miR-145a-5p modified M2 type microglia promotes the tissue repair of spinal cord injury in mice. J Transl Med. 2024 Aug 5;22(1):724
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory