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Taf2 Gene Detail
Summary
  • Symbol
    Taf2
  • Name
    TATA-box binding protein associated factor 2
  • Synonyms
    150kDa, 4732460C16Rik, CIF150, TAF2B, TAFII150
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443028
    NCBI Gene: 319944
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:54878527-54935548 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 21.96 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    287 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443028
 protein coding gene Chr15:54878525-54935580 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021851
 protein coding gene Chr15:54082545-54141577 (-)
A/J MGP_AJ_G0021811
 protein coding gene Chr15:51938556-51995724 (-)
AKR/J MGP_AKRJ_G0021792
 protein coding gene Chr15:53408049-53470053 (-)
BALB/cJ MGP_BALBcJ_G0021818
 protein coding gene Chr15:52161218-52218100 (-)
C3H/HeJ MGP_C3HHeJ_G0021592
 protein coding gene Chr15:53494952-53553969 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022257
 protein coding gene Chr15:56188734-56263898 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019794
 protein coding gene Chr15:49172665-49230195 (-)
CAST/EiJ MGP_CASTEiJ_G0021109
 protein coding gene Chr15:54082783-54144316 (-)
CBA/J MGP_CBAJ_G0021561
 protein coding gene Chr15:58171918-58228831 (-)
DBA/2J MGP_DBA2J_G0021685
 protein coding gene Chr15:51832750-51889241 (-)
FVB/NJ MGP_FVBNJ_G0021663
 protein coding gene Chr15:50953931-51028975 (-)
LP/J MGP_LPJ_G0021755
 protein coding gene Chr15:53878778-53940292 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021687
 protein coding gene Chr15:63262398-63328478 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022280
 protein coding gene Chr15:53756779-53815537 (-)
PWK/PhJ MGP_PWKPhJ_G0020854
 protein coding gene Chr15:51903701-51962491 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020691
 protein coding gene Chr15:53500336-53562231 (-)
WSB/EiJ MGP_WSBEiJ_G0021164
 protein coding gene Chr15:53739244-53815286 (-)



Homology
more
  • Human Ortholog
    TAF2, TATA-box binding protein associated factor 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TAF2, TATA-box binding protein associated factor 2
  • Synonyms
    CIF150, MRT40, TAF2B, TAFII150
  • Links
    NCBI Gene ID: 6873
    neXtProt AC: NX_Q6P1X5
    UniProt: Q6P1X5

  • Chr Location
    8q24.12; chr8:119730774-119832863 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TAF2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    732
  • Tissues
    16
  • cDNA Data
    97
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037343 Ensembl Gene Model | MGI Sequence Detail 57022 C57BL/6J ±  kb
    transcript ENSMUST00000041733 Ensembl | MGI Sequence Detail 5031 Not Applicable  
    polypeptide ENSMUSP00000043733 Ensembl | MGI Sequence Detail 1198 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000016025 transcription initiation factor TFIID subunit 2
      (term hierarchy)
    • InterPro Domains
      IPR042097 Aminopeptidase N-like , N-terminal domain superfamliy
      IPR016024 Armadillo-type fold
      IPR027268 Peptidase M4/M1, CTD superfamily
      IPR037813 Transcription initiation factor TFIID subunit 2
    Molecular
    Reagents
    less
    • All nucleic 98
      cDNA 97
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2145997
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 5
      Diseases 1
      Gene Ontology 7
      Phenotypes 18
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345548 Scheer E, et al., TAF8 regions important for TFIID lobe B assembly or for TAF2 interactions are required for embryonic stem cell survival. J Biol Chem. 2021 Oct 9;297(5):101288
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory