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Glis1 Gene Detail
Summary
  • Symbol
    Glis1
  • Name
    GLIS family zinc finger 1
  • Synonyms
    GliH1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2386723
    NCBI Gene: 230587
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:107291788-107492258 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 50.18 cM, cytoband C6
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    5759 from dbSNP Build 142
  • Strain Annotations
    22
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2386723
 protein coding gene Chr4:107283840-107492258 (+)
129S1/SvImJ ENSMUSG00200046596
 protein coding gene Chr4:102356280-102478500 (+)
A/J ENSMUSG00195043050
 protein coding gene Chr4:102899167-103021395 (+)
AKR/J ENSMUSGG00220054738
 protein coding gene Chr4:102429338-102496919 (+)
AKR/J ENSMUSG00220010877
 protein coding gene Chr4:102303598-102425638 (+)
BALB/cJ ENSMUSGG00180055557
 protein coding gene Chr4:101866046-101933510 (+)
BALB/cJ ENSMUSG00180043083
 protein coding gene Chr4:101739594-101862328 (+)
C3H/HeJ ENSMUSG00175038935
 protein coding gene Chr4:102744068-102866792 (+)
C3H/HeJ ENSMUSGG00175054651
 protein coding gene Chr4:102870510-102937971 (+)
C57BL/6NJ ENSMUSGG00215055459
 protein coding gene Chr4:102756902-102824355 (+)
C57BL/6NJ ENSMUSG00215016208
 protein coding gene Chr4:102624915-102753183 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026253
 protein coding gene Chr4:99529610-99721577 (+)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054740
 protein coding gene Chr4:102503575-102571037 (+)
CBA/J ENSMUSG00210052716
 protein coding gene Chr4:102377112-102499857 (+)
DBA/2J ENSMUSG00185049978
 protein coding gene Chr4:103079187-103207413 (+)
DBA/2J ENSMUSGG00185057498
 protein coding gene Chr4:103211132-103278573 (+)
FVB/NJ ENSMUSG00205014851
 protein coding gene Chr4:101310835-101433051 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230007729
 protein coding gene Chr4:106392727-106514954 (+)
NOD/ShiLtJ ENSMUSGG00190054529
 protein coding gene Chr4:101873346-101940807 (+)
NOD/ShiLtJ ENSMUSG00190045288
 protein coding gene Chr4:101746883-101869628 (+)
NZO/HlLtJ ENSMUSG00225032700
 protein coding gene Chr4:111497769-111625990 (+)
NZO/HlLtJ ENSMUSGG00225055444
 protein coding gene Chr4:111629709-111697157 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    GLIS1, GLIS family zinc finger 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GLIS1, GLIS family zinc finger 1
  • Links
    NCBI Gene ID: 148979
    UniProt: Q8NBF1

  • Chr Location
    1p32.3; chr1:53506232-53739164 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    12 phenotype references
Homozygous mice do not exhibit any overt abnormalities, including behavior, kidney or tooth morphology, up to 6 months of age.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    900
  • Tissues
    231
  • cDNA Data
    17
  • Literature Summary
    9
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034762 Ensembl Gene Model | MGI Sequence Detail 200471 C57BL/6J ±  kb
transcript ENSMUST00000046005 Ensembl | MGI Sequence Detail 2906 Not Applicable  
polypeptide ENSMUSP00000035650 Ensembl | MGI Sequence Detail 789 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 17
    Primer pair 3
    Other 4
    Antibodies 1

    Microarray probesets 2
References
more
  • Summaries
    All 48
    Developmental Gene Expression 9
    Gene Ontology 9
    Phenotypes 12
  • Earliest
    J:75457 Zhang F, et al., Characterization of Glis2, a novel gene encoding a Gli-related, Kruppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis. J Biol Chem. 2002 Mar 22;277(12):10139-49
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory