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Ndufs2 Gene Detail
Summary
  • Symbol
    Ndufs2
  • Name
    NADH:ubiquinone oxidoreductase core subunit S2
  • Synonyms
    MGC:27667
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385112
    NCBI Gene: 226646
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr1:171062422-171078956 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 79.25 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    306 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385112
 protein coding gene Chr1:171062422-171078957 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016749
 protein coding gene Chr1:177015975-177035400 (-)
A/J MGP_AJ_G0016729
 protein coding gene Chr1:169816130-169832744 (-)
AKR/J MGP_AKRJ_G0016695
 protein coding gene Chr1:174903460-174921573 (-)
BALB/cJ MGP_BALBcJ_G0016690
 protein coding gene Chr1:170298756-170315930 (-)
C3H/HeJ MGP_C3HHeJ_G0016513
 protein coding gene Chr1:175148307-175165124 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017151
 protein coding gene Chr1:182899115-182918945 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014859
 protein coding gene Chr1:161496366-161513021 (-)
CAST/EiJ MGP_CASTEiJ_G0016094
 protein coding gene Chr1:174770984-174790077 (-)
CBA/J MGP_CBAJ_G0016488
 protein coding gene Chr1:189416450-189435564 (-)
DBA/2J MGP_DBA2J_G0016595
 protein coding gene Chr1:168655801-168672871 (-)
FVB/NJ MGP_FVBNJ_G0016591
 protein coding gene Chr1:167003950-167020487 (-)
LP/J MGP_LPJ_G0016666
 protein coding gene Chr1:178136579-178155634 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016618
 protein coding gene Chr1:196698806-196717920 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017188
 protein coding gene Chr1:174774371-174790863 (-)
PWK/PhJ MGP_PWKPhJ_G0015880
 protein coding gene Chr1:167878138-167894922 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015664
 protein coding gene Chr1:173559083-173575379 (-)
WSB/EiJ MGP_WSBEiJ_G0016156
 protein coding gene Chr1:174891349-174907951 (-)



Homology
more
  • Human Ortholog
    NDUFS2, NADH:ubiquinone oxidoreductase core subunit S2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFS2, NADH:ubiquinone oxidoreductase core subunit S2
  • Synonyms
    CI-49, LHONAR2, MC1DN6
  • Links
    NCBI Gene ID: 4720
    neXtProt AC: NX_O75306
    UniProt: O75306

  • Chr Location
    1q23.3; chr1:161197104-161214723 (+)  GRCh38
Human Diseases
more
  • Diseases
    5 with human NDUFS2 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    46
  • GO References
    17
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    808
  • Tissues
    100
  • cDNA Data
    315
  • Literature Summary
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 226646 NCBI Gene Model | MGI Sequence Detail 16535 C57BL/6J ±  kb
transcript NM_153064 RefSeq | MGI Sequence Detail 1603 C57BL/6  
polypeptide Q91WD5 UniProt | EBI | MGI Sequence Detail 463 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 320
    cDNA 315
    Primer pair 5

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138402
References
more
  • Summaries
    All 56
    Developmental Gene Expression 7
    Gene Ontology 17
    Phenotypes 15
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory