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Glmn Gene Detail
Summary
  • Symbol
    Glmn
  • Name
    glomulin, FKBP associated protein
  • Synonyms
    9330160J16Rik, Fap48, Fap68
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141180
    NCBI Gene: 170823
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:107696833-107745754 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 52.23 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    166 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141180
 protein coding gene Chr5:107696828-107745754 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029842
 protein coding gene Chr5:109594880-109639735 (-)
A/J MGP_AJ_G0029806
 protein coding gene Chr5:105386696-105430930 (-)
AKR/J MGP_AKRJ_G0029751
 protein coding gene Chr5:108788223-108830089 (-)
BALB/cJ MGP_BALBcJ_G0029818
 protein coding gene Chr5:106519750-106562661 (-)
C3H/HeJ MGP_C3HHeJ_G0029540
 protein coding gene Chr5:109238786-109279842 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030272
 protein coding gene Chr5:114078137-114122995 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027506
 protein coding gene Chr5:100456318-100492783 (-)
CAST/EiJ MGP_CASTEiJ_G0028954
 protein coding gene Chr5:108177831-108227683 (-)
CBA/J MGP_CBAJ_G0029508
 protein coding gene Chr5:117918289-117959894 (-)
DBA/2J MGP_DBA2J_G0029654
 protein coding gene Chr5:105521932-105567335 (-)
FVB/NJ MGP_FVBNJ_G0029611
 protein coding gene Chr5:104252633-104298227 (-)
LP/J MGP_LPJ_G0029742
 protein coding gene Chr5:110176591-110222379 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029643
 protein coding gene Chr5:122829321-122873048 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030306
 protein coding gene Chr5:108351517-108395630 (-)
PWK/PhJ MGP_PWKPhJ_G0028667
 protein coding gene Chr5:104326632-104373181 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028505
 protein coding gene Chr5:105873348-105912244 (-)
WSB/EiJ MGP_WSBEiJ_G0029027
 protein coding gene Chr5:108652561-108698362 (-)



Homology
more
  • Human Ortholog
    GLMN, glomulin, FKBP associated protein
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GLMN, glomulin, FKBP associated protein
  • Synonyms
    FAP, FAP48, FAP68, FKBPAP, GLML, GVM, VMGLOM
  • Links
    NCBI Gene ID: 11146
    neXtProt AC: NX_Q92990
    UniProt: Q92990

  • Chr Location
    1p22.1; chr1:92246402-92370844 (-)  GRCh38
Human Diseases
more
  • Diseases
    3 with human GLMN associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    31 phenotypes from 3 alleles in 3 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit complete embryonic lethality during organogenesis associated with growth retardation, delayed neural tube closure, incomplete embryo turning, pericardial effusion, disorganized yolk sac vascular plexus and head mesenchyme hypocellularity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    764
  • Tissues
    49
  • cDNA Data
    11
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000029276 Ensembl Gene Model | MGI Sequence Detail 48922 C57BL/6J ±  kb
    transcript ENSMUST00000078021 Ensembl | MGI Sequence Detail 2015 Not Applicable  
    polypeptide ENSMUSP00000077168 Ensembl | MGI Sequence Detail 596 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 11
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 3
      Gene Ontology 6
      Phenotypes 17
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:309727 Rios JJ, et al., Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice. J Bone Miner Res. 2021 Aug;36(8):1548-1565
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory