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Pard6b Gene Detail
Summary
  • Symbol
    Pard6b
  • Name
    par-6 family cell polarity regulator beta
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135605
    NCBI Gene: 58220
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:167922924-167943123 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 88.24 cM, cytoband H3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    635 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135605
 protein coding gene Chr2:167922924-167943123 (+)
129S1/SvImJ ENSMUSG00200039495
 protein coding gene Chr2:164814710-164835078 (+)
A/J ENSMUSG00195024749
 protein coding gene Chr2:165152484-165172683 (+)
AKR/J ENSMUSG00220031300
 protein coding gene Chr2:164459816-164480014 (+)
BALB/cJ ENSMUSG00180035483
 protein coding gene Chr2:164606068-164626267 (+)
C3H/HeJ ENSMUSG00175036023
 protein coding gene Chr2:165377943-165398142 (+)
C57BL/6NJ ENSMUSG00215024692
 protein coding gene Chr2:164800852-164821051 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024715
 protein coding gene Chr2:160012394-160032510 (+)
CAST/EiJ ENSTCUG00005008534
 protein coding gene Chr2:163685986-163706379 (+)
CBA/J ENSMUSG00210035676
 protein coding gene Chr2:165286400-165306599 (+)
DBA/2J ENSMUSG00185025126
 protein coding gene Chr2:165000165-165020364 (+)
FVB/NJ ENSMUSG00205022491
 protein coding gene Chr2:164032868-164053067 (+)
JF1/MsJ ENSUMUG00000029676
 protein coding gene Chr2:164645136-164665305 (+)
LP/J ENSMUSG00230009272
 protein coding gene Chr2:166575480-166595846 (+)
NOD/ShiLtJ ENSMUSG00190035307
 protein coding gene Chr2:164691339-164711538 (+)
NZO/HlLtJ ENSMUSG00225001768
 protein coding gene Chr2:174573023-174593222 (+)
PWK/PhJ ENSLUMG00010033827
 protein coding gene Chr2:164547342-164567457 (+)
SPRET/EiJ ENSMSPG00010024817
 protein coding gene Chr2:167303363-167323616 (+)
WSB/EiJ ENSIUOG00005023043
 protein coding gene Chr2:164403682-164424075 (+)



Homology
more
  • Human Ortholog
    PARD6B, par-6 family cell polarity regulator beta
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PARD6B, par-6 family cell polarity regulator beta
  • Synonyms
    PAR6B
  • Links
    NCBI Gene ID: 84612
    UniProt: Q9BYG5

  • Chr Location
    20q13.13; chr20:50731382-50756795 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    666
  • Tissues
    21
  • cDNA Data
    41
  • Literature Summary
    41
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 58220 NCBI Gene Model | MGI Sequence Detail 20200 C57BL/6J ±  kb
transcript NM_021409 RefSeq | MGI Sequence Detail 3409 C57BL/6  
polypeptide Q9JK83 UniProt | EBI | MGI Sequence Detail 371 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 42
    cDNA 41
    Primer pair 1
    Antibodies 4

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139240
References
more
  • Summaries
    All 84
    Developmental Gene Expression 41
    Gene Ontology 12
    Phenotypes 6
  • Earliest
    J:63704 Lin D, et al., A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity. Nat Cell Biol. 2000 Aug;2(8):540-7
  • Latest
    J:377499 Choi HS, et al., SHANK2 establishes auditory hair bundle architecture essential for mammalian hearing. Proc Natl Acad Sci U S A. 2025 Jul 15;122(28):e2426646122
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory