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Pcdhga1 Gene Detail
Summary
  • Symbol
    Pcdhga1
  • Name
    protocadherin gamma subfamily A, 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1935212
    NCBI Gene: 93709
  • Member of
    Pcdhg cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:37794846-37974926 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.54 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5278 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1935212
 protein coding gene Chr18:37794828-37974926 (+)
129S1/SvImJ ENSMUSGG00200054410
 protein coding gene Chr18:34794210-34797456 (+)
A/J ENSMUSGG00195055112
 protein coding gene Chr18:34945290-34948536 (+)
AKR/J ENSMUSGG00220054805
 protein coding gene Chr18:34914844-34918090 (+)
BALB/cJ ENSMUSGG00180055082
 protein coding gene Chr18:35394922-35398168 (+)
C3H/HeJ ENSMUSGG00175054626
 protein coding gene Chr18:34910279-34913525 (+)
C57BL/6NJ ENSMUSGG00215055388
 protein coding gene Chr18:34664377-34667623 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022181
 protein coding gene Chr18:34845814-35028291 (+)
CAST/EiJ ENSTCUGG00005054074
 protein coding gene Chr18:34526380-34529627 (+)
CBA/J ENSMUSGG00210054603
 protein coding gene Chr18:34936932-34940178 (+)
DBA/2J ENSMUSG00185017823
 protein coding gene Chr18:34871570-34874816 (+)
FVB/NJ ENSMUSGG00205054187
 protein coding gene Chr18:34573161-34576407 (+)
JF1/MsJ ENSUMUGG00000058279
 protein coding gene Chr18:35007295-35010542 (+)
LP/J ENSMUSGG00230055535
 protein coding gene Chr18:36988356-36991602 (+)
NOD/ShiLtJ ENSMUSGG00190054507
 protein coding gene Chr18:34658614-34661860 (+)
NZO/HlLtJ ENSMUSGG00225055582
 protein coding gene Chr18:36895201-36898447 (+)
PWK/PhJ ENSLUMGG00010053895
 protein coding gene Chr18:35149656-35152902 (+)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOGG00005053976
 protein coding gene Chr18:34651007-34654253 (+)



Homology
more
  • Human Ortholog
    PCDHGA1, protocadherin gamma subfamily A, 1
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHGA1, protocadherin gamma subfamily A, 1
  • Synonyms
    PCDH-GAMMA-A1
  • Links
    NCBI Gene ID: 56114
    UniProt: Q9Y5H4

  • Chr Location
    5q31.3; chr5:141330514-141512975 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Mice homozygous for a null/reporter allele are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    620
  • Tissues
    13
  • cDNA Data
    4
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000103144 Ensembl Gene Model | MGI Sequence Detail 180081 C57BL/6J ±  kb
transcript ENSMUST00000194190 Ensembl | MGI Sequence Detail 4692 Not Applicable  
polypeptide ENSMUSP00000142062 Ensembl | MGI Sequence Detail 931 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    Genomic 2
    cDNA 5
    Primer pair 2
    Antibodies 1
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:86878 Wu Q, et al., A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 1999 Jun 11;97(6):779-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory