About   Help   FAQ
Ak7 Gene Detail
Summary
  • Symbol
    Ak7
  • Name
    adenylate kinase 7
  • Synonyms
    4930502N02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926051
    NCBI Gene: 78801
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:105672235-105748706 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 55.95 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2390 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926051
 protein coding gene Chr12:105670115-105748706 (+)
129S1/SvImJ ENSMUSG00200024197
 protein coding gene Chr12:97442138-97518699 (+)
A/J ENSMUSG00195016956
 protein coding gene Chr12:100004173-100080753 (+)
AKR/J ENSMUSG00220038486
 protein coding gene Chr12:97881642-97958230 (+)
BALB/cJ ENSMUSG00180034555
 protein coding gene Chr12:99193082-99269303 (+)
C3H/HeJ ENSMUSG00175030226
 protein coding gene Chr12:101821549-101898090 (+)
C57BL/6NJ ENSMUSG00215039961
 protein coding gene Chr12:98478022-98554617 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018092
 protein coding gene Chr12:100168256-100245497 (+)
CAST/EiJ ENSTCUG00005017607
 protein coding gene Chr12:97931028-98004265 (+)
CBA/J ENSMUSG00210013906
 protein coding gene Chr12:98883543-98960102 (+)
DBA/2J ENSMUSG00185025485
 protein coding gene Chr12:100649203-100725746 (+)
FVB/NJ ENSMUSG00205014217
 protein coding gene Chr12:97878586-97954774 (+)
JF1/MsJ ENSUMUG00000010639
 protein coding gene Chr12:105417018-105490437 (+)
LP/J ENSMUSG00230026490
 protein coding gene Chr12:107707428-107783976 (+)
NOD/ShiLtJ ENSMUSG00190024652
 protein coding gene Chr12:87255244-87331808 (-)
NZO/HlLtJ ENSMUSG00225037114
 protein coding gene Chr12:109448167-109524346 (+)
PWK/PhJ ENSLUMG00010012342
 protein coding gene Chr12:98884229-98960877 (+)
SPRET/EiJ ENSMSPG00010017520
 protein coding gene Chr12:101180970-101256233 (+)
WSB/EiJ ENSIUOG00005008682
 protein coding gene Chr12:97885524-97962078 (+)



Homology
more
  • Human Ortholog
    AK7, adenylate kinase 7
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AK7, adenylate kinase 7
  • Synonyms
    AK 7, CFAP75, FAP75, SPGF27
  • Links
    NCBI Gene ID: 122481
    UniProt: Q96M32

  • Chr Location
    14q32.2; chr14:96392128-96490031 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Ak7 mouse models; 1 with human AK7 associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    2 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 2 alleles in 2 genetic backgrounds
    16 phenotypes from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mice exhibit hydrocephalus, rhinitis, sperm defects and most die before 8 weeks of age.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    611
  • Tissues
    7
  • cDNA Data
    6
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041323 Ensembl Gene Model | MGI Sequence Detail 76472 C57BL/6J ±  kb
    transcript ENSMUST00000040876 Ensembl | MGI Sequence Detail 3099 Not Applicable  
    polypeptide ENSMUSP00000043145 Ensembl | MGI Sequence Detail 723 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 6
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 1
      Diseases 2
      Gene Ontology 10
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory