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Ccdc18 Gene Detail
Summary
  • Symbol
    Ccdc18
  • Name
    coiled-coil domain containing 18
  • Synonyms
    1700021E15Rik, 4932411G06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922974
    NCBI Gene: 73254
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:108280741-108381494 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 52.55 cM, cytoband E5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2242 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922974
 protein coding gene Chr5:108280583-108388378 (+)
129S1/SvImJ ENSMUSG00200023119
 protein coding gene Chr5:102025434-102130891 (+)
A/J ENSMUSG00195033879
 protein coding gene Chr5:101486717-101587672 (+)
AKR/J ENSMUSG00220043403
 protein coding gene Chr5:101034638-101135574 (+)
BALB/cJ ENSMUSG00180033229
 protein coding gene Chr5:101639600-101740521 (+)
C3H/HeJ ENSMUSG00175039610
 protein coding gene Chr5:103675508-103776470 (+)
C57BL/6NJ ENSMUSG00215014553
 protein coding gene Chr5:101683680-101784449 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027515
 protein coding gene Chr5:101029458-101127679 (+)
CAST/EiJ ENSTCUG00005021940
 protein coding gene Chr5:100918896-101019902 (+)
CBA/J ENSMUSG00210043968
 protein coding gene Chr5:102433072-102534032 (+)
DBA/2J ENSMUSG00185045167
 protein coding gene Chr5:105342961-105443922 (+)
FVB/NJ ENSMUSG00205038404
 protein coding gene Chr5:101355709-101456674 (+)
JF1/MsJ ENSUMUG00000011397
 protein coding gene Chr5:108398380-108505831 (+)
LP/J ENSMUSG00230031490
 protein coding gene Chr5:109566507-109671948 (+)
NOD/ShiLtJ ENSMUSG00190032954
 protein coding gene Chr5:101339165-101440107 (+)
NZO/HlLtJ ENSMUSG00225024527
 protein coding gene Chr5:117188357-117293810 (+)
PWK/PhJ ENSLUMG00010015065
 protein coding gene Chr5:100390369-100493505 (+)
SPRET/EiJ ENSMSPG00010039907
 protein coding gene Chr5:103492611-103591364 (+)
WSB/EiJ ENSIUOG00005043575
 protein coding gene Chr5:104062583-104163547 (+)



Homology
more
  • Human Ortholog
    CCDC18, coiled-coil domain containing 18
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC18, coiled-coil domain containing 18
  • Synonyms
    NY-SAR-41
  • Links
    NCBI Gene ID: 343099
    UniProt: Q5T9S5

  • Chr Location
    1p22.1; chr1:93179895-93279048 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    20
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000056531 Ensembl Gene Model | MGI Sequence Detail 100754 C57BL/6J ±  kb
    transcript ENSMUST00000047677 Ensembl | MGI Sequence Detail 5336 Not Applicable  
    polypeptide ENSMUSP00000036507 Ensembl | MGI Sequence Detail 1455 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 20

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1920504
    References
    more
    • Summaries
      All 44
      Gene Ontology 4
      Phenotypes 17
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory