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Triap1 Gene Detail
Summary
  • Symbol
    Triap1
  • Name
    TP53 regulated inhibitor of apoptosis 1
  • Synonyms
    1810015M01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916326
    NCBI Gene: 69076
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:115479290-115481612 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 56.06 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    38 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916326
protein coding gene Chr5:115479284-115481628 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029967
protein coding gene Chr5:118192180-118194522 (+)
A/J MGP_AJ_G0029932
protein coding gene Chr5:113506731-113509069 (+)
AKR/J MGP_AKRJ_G0029870
protein coding gene Chr5:117147752-117150457 (+)
BALB/cJ MGP_BALBcJ_G0029943
protein coding gene Chr5:114902814-114905150 (+)
C3H/HeJ MGP_C3HHeJ_G0029662
protein coding gene Chr5:117646894-117649233 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030397
protein coding gene Chr5:122756203-122758547 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027624
protein coding gene Chr5:108282046-108284792 (+)
CAST/EiJ MGP_CASTEiJ_G0029071
protein coding gene Chr5:116570298-116572629 (+)
CBA/J MGP_CBAJ_G0029630
protein coding gene Chr5:127472238-127474577 (+)
DBA/2J MGP_DBA2J_G0029780
protein coding gene Chr5:113580081-113582445 (+)
FVB/NJ MGP_FVBNJ_G0029736
protein coding gene Chr5:112398300-112400639 (+)
LP/J MGP_LPJ_G0029868
protein coding gene Chr5:118766488-118768824 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029767
protein coding gene Chr5:131787566-131789902 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030438
protein coding gene Chr5:116607267-116609609 (+)
PWK/PhJ MGP_PWKPhJ_G0028784
protein coding gene Chr5:112242323-112244653 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028622
protein coding gene Chr5:114166960-114169481 (+)
WSB/EiJ MGP_WSBEiJ_G0029146
protein coding gene Chr5:117205416-117207757 (+)



Homology
more
  • Human Ortholog
    TRIAP1, TP53 regulated inhibitor of apoptosis 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIAP1, TP53 regulated inhibitor of apoptosis 1
  • Synonyms
    HSPC132, MDM35, P53CSV, WF-1
  • Links
    NCBI Gene ID: 51499
    neXtProt AC: NX_O43715
    UniProt: O43715

  • Chr Location
    12q24.31; chr12:120443964-120446384 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    6
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Triap1
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69076 NCBI Gene Model | MGI Sequence Detail 2323 C57BL/6J ±  kb
transcript NM_026933 RefSeq | MGI Sequence Detail 1066 C57BL/6  
polypeptide Q9D8Z2 UniProt | EBI | MGI Sequence Detail 76 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000016637 TP53-regulated inhibitor of apoptosis 1
  • InterPro Domains
    IPR007918 Mitochondrial distribution/morphology family 35/apoptosis
Molecular
Reagents
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  • All nucleic 73
    cDNA 72
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGI:2141053, MGI:2141091
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:344404 Ma J, et al., CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise. Cell Rep. 2023 Dec 28;43(1):113626

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory