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Rab32 Gene Detail
Summary
  • Symbol
    Rab32
  • Name
    RAB32, member RAS oncogene family
  • Synonyms
    2810011A17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915094
    NCBI Gene: 67844
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:10420783-10433951 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 3.44 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    72 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915094
 protein coding gene Chr10:10420746-10434009 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017009
 protein coding gene Chr10:7910824-7924706 (-)
A/J MGP_AJ_G0016987
 protein coding gene Chr10:7539597-7553635 (-)
AKR/J MGP_AKRJ_G0016951
 protein coding gene Chr10:7722369-7735554 (-)
BALB/cJ MGP_BALBcJ_G0016945
 protein coding gene Chr10:7504297-7538228 (-)
C3H/HeJ MGP_C3HHeJ_G0016770
 protein coding gene Chr10:7890010-7904235 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017407
 protein coding gene Chr10:8090044-8103230 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015112
 protein coding gene Chr10:6971792-6984828 (-)
CAST/EiJ MGP_CASTEiJ_G0016352
 protein coding gene Chr10:7765546-7780718 (-)
CBA/J MGP_CBAJ_G0016742
 protein coding gene Chr10:8375288-8388400 (-)
DBA/2J MGP_DBA2J_G0016850
 protein coding gene Chr10:7456360-7469602 (-)
FVB/NJ MGP_FVBNJ_G0016845
 protein coding gene Chr10:7385756-7398991 (-)
LP/J MGP_LPJ_G0016925
 protein coding gene Chr10:7708291-7723335 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016875
 protein coding gene Chr10:8261774-8274924 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017445
 protein coding gene Chr10:7669244-7683974 (-)
PWK/PhJ MGP_PWKPhJ_G0016137
 protein coding gene Chr10:7391745-7405414 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015920
 protein coding gene Chr10:7718914-7731941 (-)
WSB/EiJ MGP_WSBEiJ_G0016414
 protein coding gene Chr10:7662706-7675859 (-)



Homology
more
  • Human Ortholog
    RAB32, RAB32, member RAS oncogene family
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB32, RAB32, member RAS oncogene family
  • Links
    NCBI Gene ID: 10981
    neXtProt AC: NX_Q13637
    UniProt: Q13637

  • Chr Location
    6q24.3; chr6:146543833-146554953 (+)  GRCh38
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous dendritic cell-specific conditional knockout results in increased pathogen load in liver and spleen after bacterial infection. It also increases susceptibility to, and morbidity and mortality of, DSS-induced colitis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    41
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    7
  • cDNA Data
    38
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67844 NCBI Gene Model | MGI Sequence Detail 13169 C57BL/6J ±  kb
    transcript NM_026405 RefSeq | MGI Sequence Detail 2054 NOD  
    polypeptide Q9CZE3 UniProt | EBI | MGI Sequence Detail 223 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 40
      cDNA 38
      Primer pair 1
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2143743
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 9
      Phenotypes 11
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:341218 Noda K, et al., Characterization of Rab32- and Rab38-positive lysosome-related organelles in osteoclasts and macrophages. J Biol Chem. 2023 Aug 23;299(10):105191
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory