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Fam210a Gene Detail
Summary
  • Symbol
    Fam210a
  • Name
    family with sequence similarity 210, member A
  • Synonyms
    4933403F05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914000
    NCBI Gene: 108654
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:68393258-68433404 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 40.98 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    212 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914000
 protein coding gene Chr18:68393248-68433404 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024533
 protein coding gene Chr18:68606088-68647603 (-)
A/J MGP_AJ_G0024500
 protein coding gene Chr18:65625101-65665578 (-)
AKR/J MGP_AKRJ_G0024471
 protein coding gene Chr18:67540603-67580992 (-)
BALB/cJ MGP_BALBcJ_G0024500
 protein coding gene Chr18:65788713-65830109 (-)
C3H/HeJ MGP_C3HHeJ_G0024268
 protein coding gene Chr18:67679166-67720291 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024946
 protein coding gene Chr18:70396441-70439616 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022377
 protein coding gene Chr18:64977654-65020361 (-)
CAST/EiJ MGP_CASTEiJ_G0023741
 protein coding gene Chr18:67716857-67761956 (-)
CBA/J MGP_CBAJ_G0024237
 protein coding gene Chr18:72823744-72863899 (-)
DBA/2J MGP_DBA2J_G0024367
 protein coding gene Chr18:65247358-65287961 (-)
FVB/NJ MGP_FVBNJ_G0024333
 protein coding gene Chr18:64622503-64662689 (-)
LP/J MGP_LPJ_G0024451
 protein coding gene Chr18:68465706-68505825 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024363
 protein coding gene Chr18:74076004-74135417 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024994
 protein coding gene Chr18:67705068-67745188 (-)
PWK/PhJ MGP_PWKPhJ_G0023485
 protein coding gene Chr18:65559252-65604548 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023289
 protein coding gene Chr18:67865249-67906609 (-)
WSB/EiJ MGP_WSBEiJ_G0023804
 protein coding gene Chr18:67621444-67662010 (-)



Homology
more
  • Human Ortholog
    FAM210A, family with sequence similarity 210 member A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM210A, family with sequence similarity 210 member A
  • Synonyms
    C18orf19, HsT2329
  • Links
    NCBI Gene ID: 125228
    neXtProt AC: NX_Q96ND0
    UniProt: Q96ND0

  • Chr Location
    18p11.21; chr18:13663347-13726663 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotypes from 2 alleles in 4 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit embryonic lethality after E9.5. Mice heterozygous for this allele exhibit decreased bone strength, compact bone thickness, compact bone volume, bone mineral density and bone ossification with increased osteoclasts.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    94
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038121 Ensembl Gene Model | MGI Sequence Detail 40147 C57BL/6J ±  kb
    transcript ENSMUST00000042852 Ensembl | MGI Sequence Detail 9651 Not Applicable  
    polypeptide ENSMUSP00000045927 Ensembl | MGI Sequence Detail 273 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 95
      cDNA 95

      Microarray probesets 9
    Other
    Accession IDs
    less
    MGI:2147190, MGI:2147365, MGI:3034565
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:302203 Wu J, et al., MicroRNA-574 regulates FAM210A expression and influences pathological cardiac remodeling. EMBO Mol Med. 2021 Feb 5;13(2):e12710
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory