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early conceptus |
embryo ectoderm |
embryo endoderm |
embryo mesoderm |
embryo mesenchyme |
extraembryonic component |
alimentary system |
auditory system |
branchial arches |
cardiovascular system |
connective tissue |
endocrine system |
exocrine system |
hemolymphoid system |
integumental system |
limbs |
liver and biliary system |
musculoskeletal system |
nervous system |
olfactory system |
reproductive system |
respiratory system |
urinary system |
visual system |
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| Transcription Start Site | Location | Distance from Gene 5'-end |
| Tssr144542 | Chr17:37355798-37355805 (+) | -1,086 bp |
| Tssr144543 | Chr17:37356702-37356711 (+) | -181 bp |
| Tssr144544 | Chr17:37356855-37356867 (+) | -27 bp |
| Tssr144545 | Chr17:37356872-37356972 (+) | 34 bp |
| Tssr144546 | Chr17:37356986-37357027 (+) | 119 bp |
| Tssr144547 | Chr17:37357447-37357492 (+) | 582 bp |
| Tssr144548 | Chr17:37360858-37360877 (+) | 3,980 bp |
| Tssr144549 | Chr17:37361020-37361033 (+) | 4,139 bp |
| Tssr144550 | Chr17:37361052-37361090 (+) | 4,183 bp |
| Tssr144551 | Chr17:37361496-37361507 (+) | 4,614 bp |
| Tssr144552 | Chr17:37361525-37361541 (+) | 4,645 bp |
| Tssr144553 | Chr17:37361688-37361698 (+) | 4,805 bp |
| Tssr144554 | Chr17:37361755-37361761 (+) | 4,870 bp |
| Tssr144555 | Chr17:37361829-37361842 (+) | 4,948 bp |
| Tssr144556 | Chr17:37361865-37361873 (+) | 4,981 bp |
| Tssr144557 | Chr17:37361941-37361954 (+) | 5,060 bp |
| Tssr144558 | Chr17:37364609-37364614 (+) | 7,724 bp |
| Tssr144559 | Chr17:37365671-37365713 (+) | 8,804 bp |
| Tssr144560 | Chr17:37368050-37368075 (+) | 11,175 bp |
| Tssr144561 | Chr17:37373562-37373599 (+) | 16,693 bp |
| Tssr144562 | Chr17:37382614-37382618 (+) | 25,728 bp |
| QTL | Genetic Location* | Genome Location (GRCm39) | Reference | QTL Note |
| Blmpf1 | Chr17, 17.25 cM | Chr17:32061652-37644775 | J:100369 | Gene expression analysis was used to identify candidate genes for bleomycin-induced pulmonary fibrorsis QTLs Blmpf1 and Blmpf2. These loci were previously mapped in an F2 cross between susceptible strain C57BL/6J and resistant strain C3Hf/Kam. Blmpf1 maps to 17.4 cM on mouse Chromosome 17 and Blmpf2 maps to 28 cM on mouse Chromosome 11. Genes mapping to the Blmpf1 interval on mouse Chromosome 17 were evaluated for lung mRNA expression in C57BL/6J and C3Hf/Kam animals with and without bleomycin treatment. Genes showing significant expression differences with P<0.001 are H2-D1 (19.09 cM), C4 (18.8 cM), Glo1 (16 cM), H2-Q7 (19.19 cM), H2-K (18.65 cM), Gabbr1 (20.4 cM), Tff2 (17 cM), Notch4 (18.72 cM), and Fkbp5 (13 cM). Genes mapping to the Blmpf2 interval on mouse Chromosome 11 were evaluated for lung mRNA expression in C57BL/6J and C3Hf/Kam animals with and without bleomycin treatment. Genes showing significant expression differences with P<0.001 are Scgb3a1 (25 cM), Trim16, Pttg1, and Gria1 (31 cM). |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/08/2026 MGI 6.24 |
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